Browsing BIO Faculty Scholarship by Subject "Macroheterogeneity"

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In Vitro Impact of FSH Glycosylation Variants on FSH Receptor-stimulated Signal Transduction and Functional Selectivity

Zarinan, Teresa; Butnev, Viktor Y.; Gutierrez-Sagal, Ruben; Maravillas-Montero, Jose Luis; Martinez-Luis, Ivan; Mejia-Dominguez, Nancy R.; Juarez-Vega, Gillermo; Bousfield, George R.; Ulloa-Aguirre, Alfredo (Oxford University Press, 2020-05)

FSH exists as different glycoforms that differ in glycosylation of the hormone-specific β-subunit. Tetra-glycosylated FSH (FSH24) and hypo-glycosylated FSH (FSH18/21) are the most abundant glycoforms found in humans. ...