Browsing BIO Faculty Scholarship by Subject "Fertility"

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Hypo-glycosylated hFSH drives ovarian follicular development more efficiently than fully-glycosylated hFSH: Enhanced transcription and PI3K and MAPK signaling

Hua, Guohua; George, Jitu W.; Clark, Kendra L.; Jonas, Kim C.; Johnson, Gillian P.; Southekal, Siddesh; Guda, Chittibabu; Hou, Xiaoying; Blum, Haley R.; Eudy, James; Butnev, Viktor Y.; Brown, Alan (Oxford University Press, 2021-06)

STUDY QUESTION Does hypo-glycosylated human recombinant FSH (hFSH18/21) have greater in vivo bioactivity that drives follicle development in vivo compared to fully-glycosylated human recombinant FSH (hFSH24)? SUMMARY ...