Browsing BIO Faculty Scholarship by Author "Yang, Shuye"
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Biological response of $Co^{2+}$ to preosteoblasts during aseptic loosening of the prosthesis
Jiang, Shengyuan; Li, Dan; Jiang, Jianha; Shang-You, Yang; Yang, Shuye (Journal of Clinical Rehabilitative Tissue Engineering Research, 2020-12-31)BACKGROUND: Aseptic loosening of prosthesis is the main long-term complication after artificial joint replacement. Metal ions have been proven to be one of the causes of aseptic loosening. How to control and mitigate aseptic ... -
Biological responses of preosteoblasts to particulate and ion forms of Co-Cr alloy
Yang, Shuye; Zhang, Kai; Li, Fangfang; Jiang, Jianhao; Jia, Tanghong; Yang, Shang-You (John Wiley & Sons, Inc., 2015-11)This study compared the particulate and ion forms of a cobalt-chrome (Co-Cr) alloy on the differentiation/activation of preosteoblasts. Mouse preosteoblasts (MC3T3-E1) were cultured in an osteoblast-induction medium in the ... -
Cobalt-chromium particles inducing preosteoblasts may aggravate periprosthetic inflammation
Jiang, Jianhao; Li, Peng; Du, Gangqiang; Liu, Hongzhi; Wang, Hui; Zhang, Kai; Yang, Shang-You; Yang, Shuye (Journal of Clinical Rehabilitative Tissue Engineering Research, 2019)BACKGROUND: Arthroplasty has been the most effective treatment for the end-stage osteoarthritis. However, aseptic loosening is the main long-term complication of arthroplasty. How to ameliorate aseptic loosening is an issue ... -
Different influence of Ti, PMMA, UHMWPE, and Co-Cr particles on peripheral blood monocytes during periprosthetic inflammation
Zhang, Kai; Yang, Shang-You; Yang, Shuye; Bai, Ling; Li, Peng; Liu, Dong; Schurman, John R.; Wooley, Paul H. (Wiley Periodicals, Inc., 2015-01)This study investigated cellular trafficking and inflammatory markers in orthopedic biomaterial particle-challenged human peripheral blood monocytes (PBMCs) using a murine immunodeficiency (SCID) model. Periprosthetic ... -
Particulate and ion forms of cobalt–chromium challenged preosteoblasts promote osteoclastogenesis and osteolysis in a murine model of prosthesis failure
Yang, Shuye; Zhang, Kai; Jiang, Jianhao; James, Bonface; Yang, Shang-You (Wiley, 2018-10-25)This study investigated the interactive behavior of the particulate and ion forms of cobalt–chromium (Co–Cr) alloy challenged preosteoblasts during the process of prosthetic implant loosening. Preosteoblasts were challenged ...