Browsing BIO Faculty Scholarship by Author "Wehbi, Vanessa"

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Partially deglycosylated equine LH preferentially activates beta-arrestin-dependent signaling at the follicle-stimulating hormone receptor

Wehbi, Vanessa; Tranchant, Thibaud; Durand, Guillaume; Musnier, Astrid; Decourtye, Jérémy; Piketty, Vincent; Butnev, Vladimir Y.; Bousfield, George R.; Crépieux, Pascale; Maurel, Marie-Christine; Reiter, Eric (The Endocrine Society, 2010-03)

Deglycosylated FSH is known to trigger poor Gαs coupling while efficiently binding its receptor. In the present study, we tested the possibility that a deglycosylated equine LH (eLHdg) might be able to selectively activate ...