Browsing BIO Faculty Scholarship by Author "Peters, Heiko"
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Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis
Herron, Bruce J.; Lu, Weining; Rao, Cherie; Liu, Shanming; Peters, Heiko; Bronson, Roderick T.; Justice, Monica J.; McDonald, J. David; Beier, David R. (Nature Publishing Group, 2002)Treatment with N-ethyl-N-nitrosourea (ENU) efficiently generates single-nucleotide mutations in mice. Along with the renewed interest in this approach, much attention has been given recently to large screens with broad ...