Browsing BIO Faculty Scholarship by Author "Jiang, Yunpeng"
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Current research in the pathogenesis of aseptic implant loosening associated with particulate wear debris
Jiang, Yunpeng; Jia, Tanghong; Wooley, Paul H.; Yang, Shang-You (Acta Orthopaedica Belgica, 2013-02)Periprosthetic osteolysis is the most common long-term complication of a total joint arthroplasty, often resulting in aseptic loosening of the implant, which occurs in up to 34% of younger implant recipients and usually ... -
Effects of Ti, PMMA, UHMWPE, and Co-Cr wear particles on differentiation and functions of bone marrow stromal cells
Jiang, Yunpeng; Jia, Tanghong; Gong, Weiming; Wooley, Paul H.; Yang, Shang-You (John Wiley and Sons, 2013-10)This study investigates the roles of orthopedic biomaterial particles [Ti-alloy, poly(methyl methacrylate) (PMMA), ultrahigh-molecular-weight polyethylene (UHMWPE), Co-Cr alloy] on the differentiation and functions of bone ... -
Naringin promotes osteoblast differentiation and effectively reverses ovariectomy-associated osteoporosis
Li, Nianhu; Jiang, Yunpeng; Wooley, Paul H.; Xu, Zhanwang; Yang, Shang-You (Springer Japan, 2013-05)BACKGROUND: Osteoporosis is a common pathological condition that influences 20 % of women over 50 years of age. This condition decreases bone strength and increases the risk of bone fracture. Naringin is a major flavonoid ... -
Titanium Particle-Challenged Osteoblasts Promote Osteoclastogenesis and Osteolysis in a Murine Model of Periprosthestic Osteolysis
Jiang, Yunpeng; Jia, Tanghong; Gong, Weiming; Wooley, Paul H.; Yang, Shang-You (Elsevier, 2013-03-19)The current study investigates the interactive behavior of titanium alloy particle-challenged osteoblastic bone marrow stromal cells (BMSCs) and macrophage lineage cells in a murine knee-prosthesis failure model. BMSCs ...