Browsing BIO Faculty Scholarship by Author "Irungu, Janet"
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Chromatofocusing fails to separate hFSH isoforms on the basis of glycan structure
Bousfield, George R.; Butnev, Vladimir Y.; Bidart, Jean-Michel; Dalpathado, Dilusha; Irungu, Janet; Desaire, Heather (American Chemical Society, 2008-02-12)Follicle-stimulating hormone (FSH) glycosylation is regulated by feedback from the gonads, resulting in an array of glycans associated with FSH preparations derived from pools of pituitary or urine extracts. FSH glycosylation ... -
Comparative glycomics of the glycoprotein follicle stimulating hormone: glycopeptide analysis of isolates from two mammalian species
Dalpathado, Dilusha S.; Irungu, Janet; Go, Eden P.; Butnev, Vladimir Y.; Norton, Katie; Bousfield, George R.; Desaire, Heather (American Chemical Society, 2006-06-21)Follicle stimulating hormone (FSH) is one of the important hormones that regulate gonadal functions. This hormone is glycosylated, and the glycans greatly influence the biological properties. In the present study the ... -
Method for characterizing sulfated glycoproteins in a glycosylation site-specific fashion, using ion pairing and tandem mass spectrometry
Irungu, Janet; Dalpathado, Dilusha S.; Go, Eden P.; Jiang, Hui; Ha, Hy-Vy; Bousfield, George R.; Desaire, Heather (American Chemical Society, 2006-01-21)Structural analysis of sulfated glycans is essential in understanding their biological significance. Here, we present a new approach to characterize sulfated glycans present on glycoproteins. The analysis is performed on ...