Now showing items 1-3 of 3

    • Cardiac hormones are c-Jun-N-Terminal Kinase 2-inhibiting peptides 

      Lane, Meghan L.; Santana, Omar; Frost, Chelsea D.; Nguyen, Jennifer P.; Guerrero, Jennifer; Skelton, William P.; Skelton, Michelle; Vesely, David L. (International Institute of Anticancer Research, 2012-03)
      Background: Four cardiac peptide hormones, namely vessel dilator, long-acting natriuretic peptide (LANP), kaliuretic peptide, and atrial natriuretic peptide (ANP) have anticancer effects. Materials and Methods: The effects ...
    • Novel dual inhibitors of vascular endothelial growth factor and VEGFR2 receptor 

      Nguyen, Jennifer P.; Frost, Chelsea D.; Lane, Meghan L.; Skelton, William P.; Skelton, Michelle; Vesely, David L. (Wiley-Blackwell, 2012-10)
      Eur J Clin Invest 2012; 42 (10): 10611067 Abstract Background Vascular endothelial growth factor (VEGF) helps control tumour growth via causing new capillaries growth in tumours. Four cardiac hormones [i.e. vessel dilator, ...
    • Potent selective inhibition of STAT 3 versus STAT 1 by cardiac hormones. 

      Lane, Meghan L.; Frost, Chelsea D.; Nguyen, Jennifer P.; Skelton, William P.; Skelton, Michelle; Vesely, David L. (Springer, 2012-12)
      Signal transducers and activators of transcription (STATs) are the final "switches" that activate gene expression patterns that lead to human malignancy. Extracellular signal-regulated kinases (ERK 1/2) activate STAT 3; ...