Browsing BIO Faculty Scholarship by Author "Bacher, A."

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Molecular characterization of HPH-1: a mouse mutant deficient in GTP cyclohydrolase I activity

Gutlich, M.; Ziegler, I.; Witter, K.; Hemmens, B.; Hultner, L.; McDonald, J. David; Werner, T.; Rodl, W.; Bacher, A. (Elsevier, 1994-09)

GTP cyclohydrolase I catalyzes the initial and rate limiting step of the biosynthesis of tetrahydrobiopterin, the cofactor for aromatic amino acid hydroxylation. The mouse mutant HPH-1, previously generated by chemical ...