Browsing BIO Faculty Scholarship by Author "Alwis, Imala D."

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Altered gene expression patterns during the initiation and promotion stages of neonatally diethylstilbestrol-induced hyperplasia/dysplasia/neoplasia in the hamster uterus

Hendry, William J. III; Hariri, Hussam Y.; Alwis, Imala D.; Gunewardena, Sumedha S.; Hendry, Isabel R. (Elsevier Inc, 2014-12)

Neonatal treatment of hamsters with diethylstilbestrol (DES) induces uterine hyperplasia/dysplasia/neoplasia (endometrial adenocarcinoma) in adult animals. We subsequently determined that the neonatal DES exposure event ...
Neonatal diethylstilbestrol exposure disrupts female reproductive tract structure/function via both direct and indirect mechanisms in the hamster

Alwis, Imala D.; Maroni, Dulce M.; Hendry, Isabel R.; Roy, Shyamal K.; May, Jeffrey V.; Leavitt, Wendell W.; Hendry, William J. III (2011-09-24)

We assessed neonatal diethylstilbestrol (DES)-induced disruption at various endocrine levels in the hamster. In particular, we used organ transplantation into the hamster cheek pouch to determine whether abnormalities ...