Browsing BIO Faculty Scholarship by Title
Now showing items 256-275 of 415
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L'apport des modèles murins à la compréhension de la phénylcétonurie humaine
(Elsevier, 1998)La phénylcétonurie est une maladie héréditaire qui résulte d'un défaut d'activité de l'enzyme phénylalanine hydroxylase. Cette maladie métabolique, une des toutes premières dont le caractère héréditaire fût démontré chez ... -
Landscape genetic inferences vary with sampling scenario for a pond-breeding amphibian
(John Wiley and Sons, 2019-04-15)A critical decision in landscape genetic studies is whether to use individuals or populations as the sampling unit. This decision affects the time and cost of sampling and may affect ecological inference. We analyzed 334 ... -
Large neutral amino acids in the treatment of phenylketonuria (PKU)
(Kluwer Academic Publishers, 2006-12)Large neutral amino acids (LNAAs) have been used on a limited number of patients with phenylketonuria (PKU) with the purpose of decreasing the influx of phenylalanine (Phe) to the brain. In earlier studies on mice with PKU ... -
LATERAL ORGAN BOUNDARIES defines a new family of DNA-binding transcription factors and can interact with specific bHLH proteins
(Oxford University Press, 2007-09-17)Conserved in a variety of evolutionarily divergent plant species, LOB DOMAIN (LBD) genes define a large, plant-specific family of largely unknown function. LBD genes have been implicated in a variety of developmental ... -
Lespedeza cuneata invasion alters soils facilitating its own growth
(Springer, 2014-08)Lespedeza cuneata (sericea) is an Asian legume introduced to the US in the 1930s for erosion control and forage, but it can strongly reduce the abundance of native grassland plants. One possible explanation for this high ... -
Linkage analysis of the hph-1 mutation and the GTP cyclohydrolase I structural gene
(Academic Press, 1999-09)Our research establishes genetic linkage between the hph-1 mutation and the GTP-CH I structural gene. Our results indicate that these two loci are within an 8 cM region with 95% confidence. This finding lends additional ... -
Local gene transfer of OPG prevents joint damage and disease progression in collagen-induced arthritis
(Hindawi, 2013-09-04)This study examined the influence of osteoprotegerin (OPG) gene transfer on a murine collagen-induced arthritis model. A single periarticular injection of AAV-OPG or AAV-LacZ on the arthritic paw successfully incorporated ... -
Local- vs. landscape-scale indirect effects of an invasive weed on native plants
(Weed Science Society of America, 2004)Insect-mediated indirect interactions between native plant species recently have been shown to be important determinants of plant performance in a number of ecological communities. However, the potential indirect effects ... -
Luteal morphology, atresia, and plasma progesterone concentrations during the reproductive cycle of two oviparous lizards, Crotaphytus collaris and Eumeces obsoletus
(John Wiley & Sons, 1987-08)From ovulation to oviposition, the corpora lutea of the oviparous lizards Crotaphytus collaris and Eumeces obsoletus exhibit three stages of luteal development: 1) luteogenesis, 2) luteal maturity, and 3) luteal regression. ... -
Macrophage polarization in IL-10 treatment of particle-induced inflammation and osteolysis
(Elsevier B.V., 2016-01)This study investigated the therapeutic influence and potential mechanism of IL-10 in ameliorating orthopedic debris particle-induced inflammation and osteolysis. A murine air pouch with bone implantation and polyethylene ... -
Mars Extant Life: What's Next? Conference Report
(Mary Ann Liebert, Inc, 2020-06-10)On November 5-8, 2019, the "Mars Extant Life: What's Next?" conference was convened in Carlsbad, New Mexico. The conference gathered a community of actively publishing experts in disciplines related to habitability and ... -
Material characterization and bioanalysis of hybrid scaffolds of carbon nanomaterial and polymer nanofibers
(ACS, 2019-03-08)The interconnected porous structures that mimic the extracellular matrix support cell growth in tissue engineering. Nanofibers generated by electrospinning can act as a vehicle for therapeutic cell delivery to a neural ... -
The mechanical and pharmacological regulation of glioblastoma cell migration in 3D matrices
(Wiley, 2019-04)The invasion of glioblastoma is a complex process based on the interactions of tumor cells and the extracellular matrix. Tumors that are engineered using biomaterials are more physiologically relevant than a two-dimensional ... -
Medicago truncatula ecotypes A17 and R108 show variations in jasmonic acid/ethylene induced resistance to Macrophomina phaseolina
(TAYLOR & FRANCIS LTD, 2012)The soilborne necrotrophic fungal pathogen Macrophomina phaseolina (Tassi) Goid causes charcoal rot disease in many economically important crops. There are no effective control methods for this disease and no completely ... -
Method for characterizing sulfated glycoproteins in a glycosylation site-specific fashion, using ion pairing and tandem mass spectrometry
(American Chemical Society, 2006-01-21)Structural analysis of sulfated glycans is essential in understanding their biological significance. Here, we present a new approach to characterize sulfated glycans present on glycoproteins. The analysis is performed on ... -
Microcarrier bioreactor culture system promotes propagation of human intervertebral disc cells
(Springer-Verlag, 2010-12)Background Cell-based tissue engineering has emerged as a potential therapy for intervertebral disc degeneration. However, propagating and maintaining high quantity and quality of the seed cells remains a challenge. Aims To ... -
Microsphere - encapsulated astrocytes expressing Ngf promote axonal growth
(Mary Ann Liebert, Inc., 2016-12)Astrocytes, the most abundant glial cells in the central nervous system, play a critical role in supporting the normal physiological function of neurons. Recent studies have revealed that astrocyte transplantation can ... -
Minimum annual survival estimates of male Cerulean Warblers (setophaga cerulea) in southwestern Michigan
(Wilson Ornithological Society, 2013-06)The Cerulean Warbler (Setophaga cerulea) is a North American landbird showing a high rate of population decline. Estimates of its annual adult survival rate are needed to evaluate its current population status. Annual ... -
Modeling control methods to manage the sylvatic plague in black-tailed prairie dog towns
(Rocky Mountain Mathematics Consortium, 2020-01-24)Black-tailed prairie dogs (Cynomys ludovicianus) are a keystone species of shortgrass and midgrass prairies, and they are essential for successful reintroduction efforts of endangered black-footed ferrets (Mustela nigripes). ... -
Modification of responses of Candida albicans to cisplatin by membrane damaging antimycotic agents
(Wiley-Blackwell Verlag GmbH, 1991-03)The genotoxic, antineoplastic platinum coordination complex, cisplatin (cis-diamminedichloroplatinum (II], exists as a positively charged aquated complex in water solution and as a neutral, nonaquated complex in saline ...