Browsing BIO Faculty Scholarship by Title
Now showing items 270-289 of 415
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Method for characterizing sulfated glycoproteins in a glycosylation site-specific fashion, using ion pairing and tandem mass spectrometry
(American Chemical Society, 2006-01-21)Structural analysis of sulfated glycans is essential in understanding their biological significance. Here, we present a new approach to characterize sulfated glycans present on glycoproteins. The analysis is performed on ... -
Microcarrier bioreactor culture system promotes propagation of human intervertebral disc cells
(Springer-Verlag, 2010-12)Background Cell-based tissue engineering has emerged as a potential therapy for intervertebral disc degeneration. However, propagating and maintaining high quantity and quality of the seed cells remains a challenge. Aims To ... -
Microsphere - encapsulated astrocytes expressing Ngf promote axonal growth
(Mary Ann Liebert, Inc., 2016-12)Astrocytes, the most abundant glial cells in the central nervous system, play a critical role in supporting the normal physiological function of neurons. Recent studies have revealed that astrocyte transplantation can ... -
Minimum annual survival estimates of male Cerulean Warblers (setophaga cerulea) in southwestern Michigan
(Wilson Ornithological Society, 2013-06)The Cerulean Warbler (Setophaga cerulea) is a North American landbird showing a high rate of population decline. Estimates of its annual adult survival rate are needed to evaluate its current population status. Annual ... -
Modeling control methods to manage the sylvatic plague in black-tailed prairie dog towns
(Rocky Mountain Mathematics Consortium, 2020-01-24)Black-tailed prairie dogs (Cynomys ludovicianus) are a keystone species of shortgrass and midgrass prairies, and they are essential for successful reintroduction efforts of endangered black-footed ferrets (Mustela nigripes). ... -
Modification of responses of Candida albicans to cisplatin by membrane damaging antimycotic agents
(Wiley-Blackwell Verlag GmbH, 1991-03)The genotoxic, antineoplastic platinum coordination complex, cisplatin (cis-diamminedichloroplatinum (II], exists as a positively charged aquated complex in water solution and as a neutral, nonaquated complex in saline ... -
Molecular and phenetic characterization of the bacterial assemblage of Hot Lake, WA, an environment with high concentrations of magnesium sulphate, and its relevance to Mars
(Cambridge University Press, 2014-01)Hot Lake (Oroville, WA) is an athalassohaline epsomite lake that can have precipitating concentrations of MgSO4 salts, mainly epsomite. Little biotic study has been done on epsomite lakes and it was unclear whether microbes ... -
Molecular characterization of HPH-1: a mouse mutant deficient in GTP cyclohydrolase I activity
(Elsevier, 1994-09)GTP cyclohydrolase I catalyzes the initial and rate limiting step of the biosynthesis of tetrahydrobiopterin, the cofactor for aromatic amino acid hydroxylation. The mouse mutant HPH-1, previously generated by chemical ... -
Molecular role of Schwann cell migration in repair and regeneration of nervous tissue
(Nova Science Publishers, Inc., 2022-10-06) -
Molecules, morphology and Mimeoma scarabs: evolutionary and taxonomic implications for a palm-associated scarab group
(John Wiley & Sons Ltd, 2015-10)Cyclocephaline scarabs, the second largest tribe of rhinoceros beetles, are important pollinators of early-diverging angiosperm families in the tropics. The evolutionary history of cyclocephaline genera is poorly resolved ... -
Mouse models of human phenylketonuria
(PubMed, 1993-08)Phenylketonuria (PKU) results from a deficiency in phenylalanine hydroxylase, the enzyme catalyzing the conversion of phenylalanine (PHE) to tyrosine. Although this inborn error of metabolism was among the first in humans ... -
Movement with meaning: integrating information into meta-ecology
(John Wiley & Sons Ltd, 2022-03-02)Fluxes of matter, energy and information over space and time contribute to ecosystems' functioning and stability. The meta-ecosystem framework addresses the dynamics of ecosystems linked by these fluxes but, to date, has ... -
A multi-tier data mining workflow to analyze the age related shift from diglycosylated- to tetra-glycosylated-FSH secretion by the anterior pituitary
(ACM, 2010)FSH is a glycoprotein hormone secreted as two major glycosylation variants by the anterior pituitary, which regulates reproduction in adults. As FSH consists of two functionally significant glycoforms, differentially ... -
Murine model of prosthesis failure for the long-term study of aseptic loosening
(Wiley Periodicals, Inc., 2007-02-02)We examined a novel mouse model of wear debris-induced prosthesis instability and osteolysis, and its application for the evaluation of therapy. A stainless steel or titanium-alloy pin was implanted into the proximal tibia ... -
Naringin promotes osteoblast differentiation and effectively reverses ovariectomy-associated osteoporosis
(Springer Japan, 2013-05)BACKGROUND: Osteoporosis is a common pathological condition that influences 20 % of women over 50 years of age. This condition decreases bone strength and increases the risk of bone fracture. Naringin is a major flavonoid ... -
Native grass establishment through seed addition in a southeast Kansas oak savanna restoration
(2013-08)Background/Question/Methods Globally, woody plant population expansion threatens savannas. Restoring savannas from woodlands can involve tree thinning, but often the herbaceous understory is non-existent and potential ... -
Negative influence of O-linked oligosaccharides of high molecular weight equine chorionic gonadotropin on its luteinizing hormone and follicle-stimulating hormone receptor-binding activities
(The Endocrine Society, 1996-06)Three equine CG (eCG) forms with identical amino acid sequences but different mol wt and monosaccharide compositions were isolated from a crude eCG preparation and designated eCG-L (low mol wt), eCG-M (medium mol wt), and ... -
Neonatal diethylstilbestrol exposure disrupts female reproductive tract structure/function via both direct and indirect mechanisms in the hamster
(2011-09-24)We assessed neonatal diethylstilbestrol (DES)-induced disruption at various endocrine levels in the hamster. In particular, we used organ transplantation into the hamster cheek pouch to determine whether abnormalities ... -
Neonatal diethylstilbestrol treatment alters the estrogen-regulated expression of both cell proliferation and apoptosis-related proto-oncogenes (c-jun, c-fos, c-myc, bax, bcl-2, and bcl-x) in the hamster uterus
(American Association for Cancer Research, 1997-04)In the Syrian hamster, neonatal diethylstilbestrol (DES) treatment and then postpubertal estrogen stimulation induces hyperplasia plus apoptosis (preneoplastic responses) and ultimately neoplasia in the endometrial epithelial ... -
Neonatal exposure to diethylstilbestrol leads to impaired action of androgens in adult male hamsters
(Elsevier, 2004-11)Neonatal treatment with diethylstilbestrol (DES) leads to disruption of spermatogenesis in adult animals after apparently normal testicular development during puberty indicating aberrant androgen action in DES-exposed adult ...