• Combining bioscaffolds and iPSCs in the treatment of neural trauma and Alzheimer’s disease 

  Brice, Ryan; Kehler, Joshua Lee; Yao, Li (Elsevier, 2021-06-04)

  The discovery of induced pluripotent stem cells (iPSCs) was a breakthrough in biological research poised to be a potential therapy in the field of regenerative medicine. The modality is a personalized therapy due to utilizing ...

• Movement with meaning: integrating information into meta-ecology 

  Little, Chelsea J.; Rizzuto, Matteo; Luhring, Thomas M.; Monk, Julia D.; Nowicki, Robert J.; Paseka, Rachel E.; Stegen, James C.; Symons, Celia C.; Taub, Frieda B.; Yen, Jian D. L. (John Wiley & Sons Ltd, 2022-03-02)

  Fluxes of matter, energy and information over space and time contribute to ecosystems' functioning and stability. The meta-ecosystem framework addresses the dynamics of ecosystems linked by these fluxes but, to date, has ...

• Keratinolytic bacteria from the feathers of wild Dark-eyed Juncos (Junco hyemalis) 

  Tran, Minh D.; Dille, John W.; Camden, Weslin L.; Brunt, Diamond; Rogers, Christopher M.; Schneegurt, Mark A. (SAGE Publications Ltd, 2022-01-27)

  We collected >300 bacterial isolates from overwintering Dark-eyed Juncos (Junco hyemalis) to find that ∼40% appear to degrade the structural protein of feathers using extracellular keratinase enzymes. A guild of bacteria ...

• Bacterial growth in brines formed by the deliquescence of salts relevant to cold arid worlds 

  Cesur, Robin M.; Ansari, Irfan M.; Chen, Fei; Clark, Benton C.; Schneegurt, Mark A. (Mary Ann Liebert, Inc., 2022-01-11)

  Hygroscopic salts at Mars' near-surface (MgSO4, (per)chlorates, NaCl) may form brines by absorbing moisture from the atmosphere at certain times through the process of deliquescence. We have previously shown strong bacterial ...

• A protein composite neural scaffold modulates astrocyte migration and transcriptome profile 

  Shippy, Teresa D.; Brice, Ryan; Yao, Li (John Wiley & Sons, Ltd, 2022-01-11)

  Bioscaffold implantation is a promising approach to facilitate the repair and regeneration of wounded neural tissue after injury to the spinal cord or peripheral nerves. However, such bioscaffold grafts currently result ...

• Cattle grazing in CRP grasslands during the nesting season: effects on avian abundance and diversity 

  Jameson, Mary Liz; Wilson, Benjamin S.; Jensen, William E.; Houseman, Gregory R.; Reichenborn, Molly M. (John Wiley & Sons, Ltd, 2021-11-07)

  The Conservation Reserve Program (CRP) is a primary tool for restoring grassland in the United States, in part as wildlife habitat, which has benefited declining grassland bird populations. Among potential mid‐contract ...

• Cattle grazing in CRP grasslands during the nesting season: Effects on avian reproduction 

  Jameson, Mary Liz; Kjaer, Esben; Reichenborn, Molly M.; Houseman, Gregory R.; Watson, E. Fraser; Kraus, Heather M.; Jensen, William E. (John Wiley and Sons, Inc., 2021-08-28)

  Bird populations in grasslands have experienced declines coinciding with loss and fragmentation of prairies. The United States Department of Agriculture (USDA)‐administered Conservation Reserve Program (CRP) is the most ...

• Differential FSH glycosylation modulates FSHR oligomerization and subsequent cAMP signaling 

  Agwuegbo, Uche C.; Colley, Emily; Albert, Anthony P.; Butnev, Vladimir Y.; Bousfield, George R.; Jonas, Kim (Frontiers Media, 2021-12-03)

  Follicle-stimulating hormone (FSH) and its target G protein-coupled receptor (FSHR) are essential for reproduction. Recent studies have established that the hypo-glycosylated pituitary FSH glycoform (FSH21/18), is more ...

• Human peripheral nerve-derived pluripotent cells can be stimulated by in vitro bone morphogenetic protein-2 

  Sun, Renyi; Jia, Tanghong; Dart, Bradley; Shrestha, Sunaina; Bretches, Morgan; Heggeness, Michael H.; Yang, Shang-You (MDPI, 2021-09-26)

  We have recently identified a population of cells within the peripheral nerves of adult rodent animals (mice and rats) that can respond to Bone Morphogenetic Protein-2 (BMP-2) exposure or physical injury to rapidly ...

• Effects of hypoxia on proliferation and apoptosis of osteosarcoma cells 

  Yang, Shang-You; Garcia, Elka S.; Xia, Will; Wang, Anyu (International Institute of Anticancer Research, 2021-09-30)

  Background: Hypoxia can happen during solid tumor growth including osteosarcoma. This study investigated the relationship of hypoxia-inducible factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) on osteosarcoma ...

• Habitat associations of carrion beetles (coleoptera: silphidae) across a full annual cycle 

  Engasser, Emmy L.; Stone, Rachel L.; Jameson, Mary Liz (Oxford University Press, 2021-03-05)

  Necrophagous insects play an important role in decomposition and nutrient recycling of decomposing vertebrates. Ecological studies of carrion-associated beetles enhance forensic investigations by providing information about ...

• Heads or tails? Dung beetle (Coleoptera: Scarabaeidae: Scarabaeinae and Aphodiinae) attraction to carrion 

  Stone, Rachel L.; Engasser, Emmy L.; Jameson, Mary Liz (Entomological Society of America, 2021-03-05)

  Necrophilous insects occupy an ecologically interesting niche because carrion is a highly desirable but ephemeral food source. Dung beetles (Coleoptera: Scarabaeidae: Scarabaeinae and Aphodiinae) within temperate regions ...

• Hypo-glycosylated hFSH drives ovarian follicular development more efficiently than fully-glycosylated hFSH: Enhanced transcription and PI3K and MAPK signaling 

  Hua, Guohua; George, Jitu W.; Clark, Kendra L.; Jonas, Kim; Johnson, Gillian P.; Southekal, Siddesh; Guda, Chittibabu; Hou, Xiaoying; Blum, Haley R.; Eudy, James; Butnev, Viktor Y.; Brown, Alan (Oxford University Press, 2021-06)

  STUDY QUESTION Does hypo-glycosylated human recombinant FSH (hFSH18/21) have greater in vivo bioactivity that drives follicle development in vivo compared to fully-glycosylated human recombinant FSH (hFSH24)? SUMMARY ...

• Predation landscapes influence migratory prey ecology and evolution 

  Sabal, Megan C.; Boyce, Mark S.; Charpentier, Corie L.; Furey, Nathan B.; Luhring, Thomas M.; Martin, Hans W.; Melnychuk, Michael C.; Srygley, Robert B.; Wagner, C. M.; Wirsing, Aaron J.; Ydenberg, Ronald C.; Palkovacs, Eric P. (Elsevier, 2021-05-13)

  Migratory prey experience spatially variable predation across their life cycle. They face unique challenges in navigating this predation landscape, which affects their perception of risk, antipredator responses, and resulting ...

• Bioscaffold-based study of glioblastoma cell behavior and drug delivery for tumor therapy 

  Tran, Kimmy; Brice, Ryan; Yao, Li (Elsevier, 2021-07-01)

  Glioblastoma multiforme (GBM) is a severe form of brain cancer with an average five-year survival rate of 6.7%. Current treatment strategies include surgical resection of the tumor area and lining the lesion site with ...

• FGDB: Database of follicle stimulating hormone glycans 

  Shakyawar, Sushil K.; Pandey, Sanjit; Harvey, David J.; Bousfield, George R.; Guda, Chittibabu (Elsevier, 2021)

  Glycomics, the study of the entire complement of sugars of an organism has received significant attention in the recent past due to the advances made in high throughput mass spectrometry technologies. These analytical ...

• Botany is the root and the future of invasion biology 

  Sutherland, Brittany L.; Barrett, Craig F.; Beck, James B.; Latvis, Maribeth; McKain, Michael R.; Sigel, Erin; Kooyers, Nicholas J. (Botanical Society of America, 2021-04-23)

  Botanists have always been at the forefront of invasion biology, from early observations to contemporary hypothesis testing with modern tools. Plants have distinct advantages as experimental systems that have and will allow ...

• Two cytotype niche shifts are of different magnitude in Solidago gigantea 

  Martino, Maria; Semple, John C.; Beck, James B. (Botanical Society of America, 2020-11-04)

  Premise: Polyploidy may serve to contribute to range size if autopolyploid cytotypes are adapted to differing ecological conditions. This study aims to establish the geographic distribution of cytotypes within the giant ...

• Biological response of $Co^{2+}$ to preosteoblasts during aseptic loosening of the prosthesis 

  Jiang, Shengyuan; Li, Dan; Jiang, Jianha; Shang-You, Yang; Yang, Shuye (Journal of Clinical Rehabilitative Tissue Engineering Research, 2020-12-31)

  BACKGROUND: Aseptic loosening of prosthesis is the main long-term complication after artificial joint replacement. Metal ions have been proven to be one of the causes of aseptic loosening. How to control and mitigate aseptic ...

• Genetic analysis of the molecular regulation of electric fields-guided glia migration 

  Yao, Li; Shippy, Teresa D.; Li, Yongchao (Nature Research, 2020-10-08)

  In a developing nervous system, endogenous electric field (EF) influence embryonic growth. We reported the EF-directed migration of both rat Schwann cells (SCs) and oligodendrocyte precursor cells (OPCs) and explored the ...

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