• Bioactivity of recombinant hFSH glycosylation variants in primary cultures of porcine granulosa cells 

  Liang, Aixin; Plewes, Michele R.; Hua, Guohua; Hou, Xiaoying; Blum, Haley R.; Przygrodzka, Emilia; George, Jitu W.; Clark, Kendra L.; Bousfield, George R.; Butnev, Viktor Y.; May, Jeffrey V.; Davis, John S. (Elsevier, 2020-06-15)

  Previous studies have reported hypo-glycosylated FSH and fully-glycosylated FSH to be naturally occurring in humans, and these glycoforms exist in changing ratios over a woman's lifespan. The precise cellular and molecular ...

• Mars Extant Life: What's Next? Conference Report 

  Schneegurt, Mark A. (Mary Ann Liebert, Inc, 2020-06-10)

  On November 5-8, 2019, the "Mars Extant Life: What's Next?" conference was convened in Carlsbad, New Mexico. The conference gathered a community of actively publishing experts in disciplines related to habitability and ...

• Effects of nitrogen and phosphorus limitation on lipid accumulation by Chlorella kessleri str. UTEX 263 grown in darkness 

  Shrestha, Nayan; Dandinpet, Kiran K.; Schneegurt, Mark A. (Springer, 2020-06-08)

  Growing algae in darkness for biodiesel production eliminates the challenges of evaporation and light penetration reported for open ponds and the costs and fouling that plague photobioreactors. The current study demonstrated ...

• Preparation of bioscaffolds delivering stem cells for neural regeneration 

  Yao, Li; DeBrot, Ashley (Humana, New York, NY, 2020-05-31)

  Bioscaffolds have been proven for their feasibility in neural repair. Neural conduits have been investigated in the repair of wounded peripheral nerve and spinal cord. These conduits support axonal growth by providing ...

• Cobalt-chromium particles inducing preosteoblasts may aggravate periprosthetic inflammation 

  Jiang, Jianhao; Li, Peng; Du, Gangqiang; Liu, Hongzhi; Wang, Hui; Zhang, Kai; Yang, Shang-You; Yang, Shuye (Journal of Clinical Rehabilitative Tissue Engineering Research, 2019)

  BACKGROUND: Arthroplasty has been the most effective treatment for the end-stage osteoarthritis. However, aseptic loosening is the main long-term complication of arthroplasty. How to ameliorate aseptic loosening is an issue ...

• Post-dispersal factors influence recruitment patterns but do not override the importance of seed limitation in populations of a native thistle 

  Rand, Tatyana A.; West, Natalie M.; Russell, F. Leland; Louda, Svata M. (Springer, 2020-04-22)

  Whether plant populations are limited by seed or microsite availability is a long-standing debate. However, since both can be important, increasing emphasis is placed on disentangling their relative importance and how they ...

• In Vitro Impact of FSH Glycosylation Variants on FSH Receptor-stimulated Signal Transduction and Functional Selectivity 

  Zarinan, Teresa; Butnev, Viktor Y.; Gutierrez-Sagal, Ruben; Maravillas-Montero, Jose Luis; Martinez-Luis, Ivan; Mejia-Dominguez, Nancy R.; Juarez-Vega, Gillermo; Bousfield, George R.; Ulloa-Aguirre, Alfredo (Oxford University Press, 2020-05)

  FSH exists as different glycoforms that differ in glycosylation of the hormone-specific β-subunit. Tetra-glycosylated FSH (FSH24) and hypo-glycosylated FSH (FSH18/21) are the most abundant glycoforms found in humans. ...

• A basic ddRADseq two‐enzyme protocol performs well with herbarium and silica‐dried tissues across four genera 

  Jordon‐Thaden, Ingrid E.; Beck, James B.; Rushworth, Catherine; Windham, Michael D.; Diaz, Nicolas; Cantley, Jason T.; Martine, Christopher T.; Rothfels, Carl J. (Wiley, 2020-04-23)

  Premise The ability to sequence genome‐scale data from herbarium specimens would allow for the economical development of data sets with broad taxonomic and geographic sampling that would otherwise not be possible. Here, ...

• Urine screening for opioid and Illicit drugs in the total joint arthropiasty population 

  Vopat, Matthw L; Messamore, William G.; Trent, Jesse J.; Schumanke, Ken E.; Zackula, Rosalee E.; Yang, Shang-You; Bhargava, Tarun (Kansas Journal of Medicine, 2020-04-17)

  Recent studies have shown an increase in post-operative orthopaedic complications associated with pre-operative opioid use. It is, therefore, important to know if patients use opioids before scheduled surgery. The purpose ...

• RNAi-mediated knockdown of β-1,3-glucan synthase suppresses growth of the phytopathogenic fungus Macrophomina phaseolina 

  Forster, Heather; Shuai, Bin (Elsevier, 2020-04)

  Charcoal rot, caused by the fungus Macrophomina phaseolina, affects wide varieties of plant species and may result in serious crop losses. Exogenous siRNAs were applied to target a β-1,3-glucan synthase (MpGLS2) gene in ...

• Modeling control methods to manage the sylvatic plague in black-tailed prairie dog towns 

  Elzinga, David C.; Stowe, Shelby R.; Russell, F. Leland (Rocky Mountain Mathematics Consortium, 2020-01-24)

  Black-tailed prairie dogs (Cynomys ludovicianus) are a keystone species of shortgrass and midgrass prairies, and they are essential for successful reintroduction efforts of endangered black-footed ferrets (Mustela nigripes). ...

• Graphis and Allographa (lichenized Ascomycota: Graphidaceae) in Sri Lanka, with six new species and a biogeographical comparison investigating a potential signature of the 'biotic ferry' species interchange 

  Weerakoon, Gothamie; Aptroot, Andre; Lucking, Robert K.; Arachchige, Omal; Wijesundara, Siril (Cambridge University Press, 2019-12-09)

  We provide an updated survey for Sri Lanka of species of Graphis sensu Staiger, recently divided into Graphis s. str. and Allographa, including brief descriptions and a key to all 124 species currently known. Six new species ...

• Recombinant FSH glycoforms are bioactive in mouse preantral ovarian follicles 

  Simon, Leah E.; Liu, Zhenghui; Bousfield, George R.; Kumar, T. Rajendra; Duncan, Francesca E. (Society for Reproduction and Fertility, 2019-12)

  Female reproductive aging is characterized by a rise in follicle-stimulating hormone (FSH) levels during peri-menopause. N-linked glycans are co-translationally attached to the Asn7 and Asn24 residues on the FSHβ subunit. ...

• Investigating MTX-Loaded magnetic nanocomposite particles for treatment of rheumatoid arthritis 

  Usta, Aybala; Man, Ka-Poh; Strong, Nora M.; Misak, Heath Edward; Wooley, Paul H.; Asmatulu, Ramazan (Elsevier B.V., 2020-04-01)

  Rheumatoid arthritis (RA) is a chronic autoimmune disorder that initially leads to inflammation in the lining of a joint and other parts of the body, then progresses and causes deformity. It occurs when the immune system ...

• A comprehensive approach to analyzing community dynamics using rank abundance curves 

  Avolio, Meghan L.; Carroll, Ian T.; Collins, Scott L.; Houseman, Gregory R.; Hallett, Lauren M.; Isbell, Forest I.; Koerner, Sally E.; Komatsu, Kimberly J.; Smith, Melinda D.; Wilcox, Kevin R. (Wiley-Blackwell, 2019-10-17)

  Univariate and multivariate methods are commonly used to explore the spatial and temporal dynamics of ecological communities, but each has limitations, including oversimplification or abstraction of communities. Rank ...

• Phenotypically plastic responses to predation risk are temperature dependent 

  Luhring, Thomas M.; Vavra, Janna M.; Cressler, Clayton E.; DeLong, John P. (Springer Verlag, 2019-11)

  Predicting how organisms respond to climate change requires that we understand the temperature dependence of fitness in relevant ecological contexts (e.g., with or without predation risk). Predation risk often induces ...

• Fabrication and characterization of a protein composite conduit for neural regeneration 

  Yao, Li; DeBrot, Ashley (American Chemical Society, 2019-09-11)

  Spinal cord injury (SCI) causes the proliferation of resident microglia and promotes cell migration. Peripheral nerve injury induces the morphological changes and proliferation macrophages. The implantation of neural ...

• An integrated simulation-optimization framework to optimize search and treatment path for controlling a biological invader 

  Onal, Sevilay; Akhundov, Najmaddin; Buyuktahtakin, Esra; Smith, Jennifer (Elsevier, 2019-10-01)

  Invasive species cause large economic losses and are difficult to control due to the high cost of locating and treating the continual emergence of new individuals. The national strategy against invasive species encompasses ...

• Global change effects on plant communities are magnified by time and the number of global change factors imposed 

  Komatsu, Kimberly J.; Avolio, Meghan L.; Lemoine, Nathan P.; Isbell, Forest I.; Grman, Emily L.; Houseman, Gregory R. (National Academy of Sciences, 2019-09-03)

  Global change drivers (GCDs) are expected to alter community structure and consequently, the services that ecosystems provide. Yet, few experimental investigations have examined effects of GCDs on plant community structure ...

• Effect of soil heterogeneity and endogenous processes on plant spatial structure 

  Schouten, Olivia S.; Houseman, Gregory R. (John Wiley and Sons, 2016-07-22)

  Within communities, organisms potentially self-organize through endogenous processes that create nonrandom spatial structure as they interact with one another or modify the abiotic environment. In contrast, exogenous ...

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