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dc.contributor.advisorNair, Rajeev
dc.contributor.authorBashir, Mahmood Al
dc.date.accessioned2017-06-01T20:00:13Z
dc.date.available2017-06-01T20:00:13Z
dc.date.issued2017-04-28
dc.identifier.citationBashir, Mahmood A. 2017. Femtosecond laser Nanotexturing of drug-eluting stents--In Proceedings: 13th Annual Symposium on Graduate Research and Scholarly Projects. Wichita, KS: Wichita State University, p.20
dc.identifier.urihttp://hdl.handle.net/10057/13266
dc.descriptionPresented to the 13th Annual Symposium on Graduate Research and Scholarly Projects (GRASP) held at the Rhatigan Student Center, Wichita State University, April 28, 2017.
dc.descriptionResearch completed in the Department of Mechanical Engineering, College of Engineering
dc.description.abstractStents have been used for over a decade to treat coronary arteries affected by stenosis, a state where the arteries are narrowed by the deposition of plaque. But studies have found restenosis can hinder its purpose. Drug-eluting stents (DES) have a significant impact in treating restenosis. DES are embedded with drugs that are released over time after stent is placed within the artery, reducing the chance of plaque deposition around the stent. But DES risks the chance of increased thrombosis, which is a state when blood clots form around the stent because of a change in the blood flow profile. In our research we used femtosecond pulsed lasers to create Nano-textured patterns on a biomaterial, Tantalum and studied the structure. The 'peaks and valley' structure found under the microscope shows potentials to be used as a drug reservoir for the stents. Further studies are being conducted to test the fluid retention characteristics of the material, which can be a cost-effective solution to reduce or completely eliminate in-stent restenosis and thrombosis without the need of post-finishing operations. The interaction of bioelements with the metallic stents are also being tested to ensure the efficiency of the DES.
dc.description.sponsorshipGraduate School, Academic Affairs, University Libraries, Regional Institute on Aging
dc.language.isoen_US
dc.publisherWichita State University
dc.relation.ispartofseriesGRASP
dc.relation.ispartofseriesv. 13
dc.titleFemtosecond laser Nanotexturing of drug-eluting stents
dc.typeAbstract
dc.rights.holderWichita State University


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