Serine protease inhibitors
Groutas, William C.
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Groutas, William C., inventor. Wichita State University, assignee. Serine protease inhibitors. United States patent US 5,550,139. 1996, Aug 27.
Isothiazolidin-3-one-1,1 dioxide, 3-oxo-1,2,5-thiadiazolidine-1,1,-dioxide and derivatives thereof, reduce or inhibit the activity of serine proteases. Such compounds are useful as anti-inflammatory and anti-metastatic agents.
WSU inventor: William C. Groutas, Dept. of Chemistry, College of Liberal Arts and Sciences
Appl. No: 08/177,352 filed Jan 3, 1994. Patent No:. U.S. 5,550,139 granted Aug 27, 1996.