Now showing items 1-20 of 34

    • 1,2,5, thiadiazolidin-3-one 1,1-dioxide derivatives 

      Groutas, William C.; Kuang, Rongze (United States Patent and Trademark Office, 2002-07-16)
      Substituted derivatives of 1,2,5-thiadiazolidin-3-one 1,1-dioxides, oligomers containing them, and methods of using them.
    • Apparatus and method for simulating machining and other forming operations 

      Madhavan, Viswanathan (United States Patent and Trademark Office, 2020-03-17)
      A method includes obtaining information associated with a forming operation involving a manufacturing machine having a tool that contacts material and simulating deformation of the material based on the information. ...
    • Apparatus and method for simulating machining and other forming operations 

      Madhavan, Viswanathan (United States Patent and Trademark Office, 2018-04-03)
      A method includes obtaining information associated with a forming operation involving a manufacturing machine having a tool that contacts material. The method also includes simulating deformation of the material based on ...
    • Autonomously guiding vehicles through orifices 

      Chakravarthy, Animesh; Ghose, Debasish (United States Patent and Trademark Office, 2020-02-25)
      This document generally describes a safe-passage guidance strategy developed in a relative velocity framework to enable a generic aerial robot execute a precision three-dimensional maneuver through a narrow orifice in a ...
    • Basketball shooting aid 

      Boatright, Darron; Reuter, Kimberly Marie; DeGarmo, Jason M. (United States Patent and Trademark Office, 2020-03-17)
      A basketball shooting aid includes a sidewall having an upper surface, a lower surface, an inner surface, and an outer surface. The upper surface of the sidewall defines an upper orifice and the lower surface of the sidewall ...
    • Beacon-based indoor wayfinding system with automated beacon placement 

      Namboodiri, Vinod; Cheraghi, Seyed Ali (United States Patent and Trademark Office, 2020-05-19)
      An automated process designs an indoor wayfinding system using wireless beacons interacting with a mobile smartphone to guide a user to a destination. Image processing and computational geometric techniques extracting ...
    • Broad-spectrum antivirals against 3C or 3C-like proteases of picornavirus-like supercluster: picornaviruses, caliciviruses and coronaviruses 

      Chang, Kyeong-Ok; Kim, Yunjeong; Groutas, William C.; Hua, Duy; Saif, Linda J. (United States Patent and Trademark Office, 2016-10-25)
      Antiviral protease inhibitors, including peptidyl aldehydes, peptidyl .alpha.-ketoamides, peptidyl bisulfate salts, and peptidyl heterocycles, are disclosed, along with related antiviral compounds, and methods of using the ...
    • Composite magnetic nanoparticle drug delivery system 

      Asmatulu, Ramazan; Misak, Heath Edward; Yang, Shang-You; Wooley, Paul H. (United States Patent and Trademark Office, 2017-10-10)
      A composite magnetic nanoparticle drug delivery system provides targeted controlled release chemotherapies for cancerous tumors and inflammatory diseases. The magnetic nanoparticle includes a biocompatible and biodegradable ...
    • Computer program, system, and method for observation and communication for mobile settings, mobile applications, and wearable mobile devices 

      He, Jibo; Chaparro, Barbara S. (United States Patent and Trademark Office, 2018-01-09)
      A system including at least first and second wearable mobile devices and optionally one or more smartphones or other computing devices for allowing a wearable mobile device wearer, an on-site observer, and a remote observer ...
    • Conversion of natural gas into clean liquid fuels 

      Gu, Shuang; Houtaham, Farshad (United States Patent and Trademark Office, 2019-12-31)
      Provided herein are methods and systems for converting natural gas, and specifically methane, into higher-value oxycarbon products, such as methanol, methyl formate, and formic acid. The natural gas is introduced into an ...
    • End effector for forming swept friction stir spot welds 

      Burford, Dwight A. (United States Patent and Trademark Office, 2013-05-21)
      An apparatus includes a connector and is configured to mount to a machine having multiple axes of control. A control signal on the connector determines a path of a rotating tool holder.
    • End effector for forming swept friction stir spot welds 

      Burford, Dwight A. (United States Patent and Trademark Office, 2015-09-15)
      An apparatus includes a connector and is configured to mount to a machine having multiple axes of control. A control signal on the connector determines a path of a rotating tool holder.
    • Energy absorbing seat mechanism 

      Olivares, Gerardo (United States Patent and Trademark Office, 2016-05-03)
      A system includes a shear member and an energy absorber. The shear member is configured to couple a seat portion to a base structure of a vehicle. The shear member is configured to sustain a first load without fracture and ...
    • Energy absorbing seat mechanism 

      Olivares, Gerardo (United States Patent and Trademark Office, 2018-05-29)
      A system includes a shear member and an energy absorber. The shear member is configured to couple a seat portion to a base structure of a vehicle. The shear member is configured to sustain a first load without fracture and ...
    • Friction stir welding tool having a counterflow pin configuration 

      Burford, Dwight A. (United States Patent and Trademark Office, 2011-05-17)
      A friction stir welding tool having one or more tapered flats for promoting flow of weld material toward the pin terminus and one or more counter-spiraling channels or threads which for promoting flow of the weld material ...
    • Friction stir welding tool having a scroll-free concentric region 

      Burford, Dwight A. (United States Patent and Trademark Office, 2011-09-13)
      A friction stir welding tool having a shoulder section with a scroll pattern that terminates prior to the edge or boundary of the shoulder section to create a scroll-free concentric surface area.
    • Latent isocynate derivatives useful for deactivating enzymes 

      Groutas, William C. (United States Patent and Trademark Office, 1990-05-29)
      Certain amino-acid derivatives are disclosed as effective inhibitors of human leukocyte elastase and therefore useful in preventing the imbalance of this proteolytic enzyme in vivo. The compounds specifically are derivatives ...
    • Macrocyclic and peptidomimetic compounds as broad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, caliciviruses and coronaviruses 

      Chang, Kyeong-Ok; Kim, Yunjeong; Groutas, William C. (United States Patent and Trademark Office, 2016-04-12)
      Antiviral protease inhibitors, including macrocylic transition state inhibitors and peptidomimetics are disclosed, along with related antiviral compounds, and methods of using the same to treat or prevent viral infection ...
    • Method and system for capture and use of intact vesicles on electrodeposited hydrophobically modified biopolymer films 

      Dowling, Matthew; Raghavan, Srinivasa R.; Dashaputre, Neeraja; English, Douglas S.; Javvaji, Vishal; Payne, Gregory F.; DeShong, Philip R. (United States Patent and Trademark Office, 2014-10-14)
      A biosensor comprising an electrically conductive substrate coated with a modified chitosan biopolymer that has been electrodeposited on the substrate, wherein said modified chitosan biopolymer comprises at least one vesicle ...
    • Non-invasive biofeedback system 

      He, Jibo; Patterson, Jeremy A. (United States Patent and Trademark Office, 2019-07-16)
      A method, system, and computer program for non-invasively monitoring a physiological parameter and providing biofeedback. The method, system, and computer program provide for the non-invasive detection of a physiological ...