Now showing items 1-2 of 2

    • Protective antigen complexes with increased stability and uses thereof 

      Bann, James G.; Miyagi, Masaru (United States Patent and Trademark Office, 2019-01-29)
      Immunogenic compositions against Bacillus anthracis comprising a stabilized protective antigen complex are disclosed. The stabilized complex comprises protective antigen protein and capillary morphogenesis protein-2, with ...
    • Protective antigen having fluorinated histidine residues 

      Bann, James G. (United States Patent and Trademark Office, 2010-06-08)
      The unnatural amino acid analogue 2-fluorohistidine (2-FHis) was incorporated into protective antigen to produce a protein which resists protonation at physiological pH by reducing the side-chain pKa. The protein structure ...