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dc.contributor.authorKephart, Wesley C.
dc.contributor.authorWachs, Taylor D.
dc.contributor.authorMac, Thompson, R.
dc.contributor.authorMobley, C. Brooks
dc.contributor.authorFox, Carlton D.
dc.contributor.authorMcDonald, James R.
dc.contributor.authorFerguson, Brian S.
dc.contributor.authorYoung, Kaelin C.
dc.contributor.authorNie, Ben
dc.contributor.authorMartin, Jeffrey S.
dc.contributor.authorCompany, Joseph M.
dc.contributor.authorPascoe, David D.
dc.contributor.authorArnold, Robert D.
dc.contributor.authorMoon, Jordan R.
dc.contributor.authorRoberts, Michael D.
dc.date.accessioned2016-03-18T14:36:00Z
dc.date.available2016-03-18T14:36:00Z
dc.date.issued2016-03
dc.identifier.citationWesley C. Kephart, Taylor D. Wachs, R. Mac Thompson, C. Brooks Mobley, Carlton D. Fox, James R. McDonald, Brian S. Ferguson, Kaelin C. Young, Ben Nie, Jeffrey S. Martin, Joseph M. Company, David D. Pascoe, Robert D. Arnold, Jordan R. Moon, Michael D. Roberts. 2016. Ten weeks of branched-chain amino acid supplementation improves select performance and immunological variables in trained cyclists. Amino Acids, March 2016:vol. 48:no. 3:pp 779-789en_US
dc.identifier.issn0939-4451
dc.identifier.otherWOS:000370817900012
dc.identifier.urihttp://dx.doi.org/10.1007/s00726-015-2125-8
dc.identifier.urihttp://hdl.handle.net/10057/11956
dc.descriptionClick on the DOI link to access the article (may not be free).en_US
dc.description.abstractWe examined if supplementing trained cyclists (32 +/- A 2 year, 77.8 +/- A 2.6 kg, and 7.4 +/- A 1.2 year training) with 12 g/day (6 g/day l-Leucine, 2 g/day l-Isoleucine and 4 g/day l-Valine) of either branched-chain amino acids (BCAAs, n = 9) or a maltodextrin placebo (PLA, n = 9) over a 10-week training season affected select body composition, performance, and/or immune variables. Before and after the 10-week study, the following was assessed: (1) 4-h fasting blood draws; (2) dual X-ray absorptiometry body composition; (3) Wingate peak power tests; and (4) 4 km time-trials. No group x time interactions existed for total lean mass (P = 0.27) or dual-leg lean mass (P = 0.96). A significant interaction existed for body mass-normalized relative peak power (19 % increase in the BCAA group pre- to post-study, P = 0.01), and relative mean power (4 % increase in the BCAA group pre- to post-study, P = 0.01). 4 km time-trial time to completion approached a significant interaction (P = 0.08), as the BCAA group improved in this measure by 11 % pre- to post-study, though this was not significant (P = 0.15). There was a tendency for the BCAA group to present a greater post-study serum BCAA: l-Tryptophan ratio compared to the PLA group (P = 0.08). A significant interaction for neutrophil number existed (P = 0.04), as there was a significant 18 % increase within the PLA group from the pre- to post-study time point (P = 0.01). Chronic BCAA supplementation improves sprint performance variables in endurance cyclists. Additionally, given that BCAA supplementation blunted the neutrophil response to intense cycling training, BCAAs may benefit immune function during a prolonged cycling season.en_US
dc.description.sponsorshipReagent costs and participant compensation costs were paid through a contract awarded to M.D.R. through MusclePharm Corp. (Denver, CO). B.N. and R.D.A were supported in part by funding from NIH R01 EB016100.en_US
dc.language.isoen_USen_US
dc.publisherSpringer Viennaen_US
dc.relation.ispartofseriesAmino Acids;v.48:no.3
dc.subjectLeucineen_US
dc.subjectIsoleucineen_US
dc.subjectValineen_US
dc.subjectCyclingen_US
dc.subjectPeak poweren_US
dc.subjectImmunityen_US
dc.titleTen weeks of branched-chain amino acid supplementation improves select performance and immunological variables in trained cyclistsen_US
dc.typeArticleen_US
dc.rights.holderCopyright © 2015, Springer-Verlag Wienen_US


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