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dc.contributor.authorGurung, Ritu
dc.contributor.authorVattepu, Ravi
dc.contributor.authorYadav, Rahul
dc.contributor.authorBeck, Moriah R.
dc.identifier.citationGurung, Ritu; Vattepu, Ravi; Yadav, Rahul; Beck, Moriah R. 2015. Palladin Nucleates Actin Assembly and Regulates Cytoskeleton Architecture. Biophysical Journal, vol. 108:no. 2, Supplement 1, 27 January 2015:pp 297aen_US
dc.descriptionClick on the DOI link to access the article (may not be free).en_US
dc.description.abstractThe actin scaffold protein palladin regulates both normal cell migration and invasive cell motility, processes that require the coordinated regulation of actin dynamics. Palladin localizes to actin-rich protrusions and has a well-documented effect on metastasis of invasive cancers. However, its potential effects on actin dynamics have remained elusive. Here, we show that the C-terminal immunoglobulin-like domain of palladin (Ig3) that is directly responsible for actin binding and bundling also potently nucleates the formation of actin filaments in vitro.en_US
dc.publisherElsevier Inc.en_US
dc.relation.ispartofseriesBiophysical Journal;v.108:no.2
dc.subjectC-terminal immunoglobulin-like domain of palladin (Ig3)en_US
dc.titlePalladin Nucleates Actin Assembly and Regulates Cytoskeleton Architectureen_US
dc.rights.holderCopyright © 2015 Biophysical Societyen_US

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