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dc.contributor.authorSeraz, Md Syef
dc.contributor.authorAsmatulu, Ramazan
dc.contributor.authorChen, Zheng
dc.contributor.authorCeylan, Muhammet
dc.contributor.authorMahapatro, Anil
dc.contributor.authorYang, Shang-You
dc.date.accessioned2014-08-08T14:59:55Z
dc.date.available2014-08-08T14:59:55Z
dc.date.issued2014-04-18
dc.identifier.citationMd. S. Seraz ; R. Asmatulu ; Z. Chen ; M. Ceylan ; A. Mahapatro, et al. " Antibacterial polyelectrolyte-coated Mg alloys for biomedical applications ", Proc. SPIE 9060, Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2014, 90600J (April 18, 2014); doi:10.1117/12.2047255en_US
dc.identifier.isbn978-0-8194-9986-8
dc.identifier.issn0277-786X
dc.identifier.urihttp://dx.doi.org/10.1117/12.2047255
dc.identifier.urihttp://hdl.handle.net/10057/10693
dc.descriptionClick on the DOI link to access the article (may not be free).en_US
dc.description.abstractThis study deals with two biomedical subjects: corrosion rates of polyelectrolyte-coated magnesium (Mg) alloys, mainly used for biomedical purposes, and antibacterial properties of these alloys. Thin sheets of Mg alloys were coated with cationic polyelectrolyte chitosan (CHI) and anionic polyelectrolyte carboxymethyl cellulose (CMC) using a layer-by-layer coating method and then embedded with antibacterial agents under vacuum. Electrochemical impedance spectroscopy was employed to analyze these samples in order to detect their corrosion properties at different conditions. In the electrochemical analysis section, a corrosion rate of 72 mille inches per year was found in a salt solution for the sample coated with a 12 phosphonic acid self-assembled monolayer and 9 CHI/CMC multilayers. In the antibacterial tests, gentamicin was used to investigate the effects of the drug embedded with the coated surfaces against the Escherichia coli (E. coli) bacteria. Antibacterial studies were tested using the disk diffusion method. Based on the standard diameter of the zone of inhibition chart, the antibacterial diffusion from the surface strongly inhibited bacterial growth in the regions. The largest recorded diameter of the zone of inhibition was 50 mm for the pre-UV treated and gentamicin-loaded sample, which is more than three times the standard diameter.en_US
dc.language.isoen_USen_US
dc.publisherSPIEen_US
dc.relation.ispartofseriesProceedings SPIE 9060, Nanosensors, Biosensors, and Info-Tech Sensors and Systems 2014;v.9060
dc.subjectMg alloyen_US
dc.subjectLBL coatingen_US
dc.subjectAntibacterialen_US
dc.subjectCardiovascular applicationsen_US
dc.titleAntibacterial polyelectrolyte-coated Mg alloys for biomedical applicationsen_US
dc.typeArticleen_US


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