Microwave heating has been gaining interest as an alternative green energy source. Similarly enzymatic assisted polymer chemistry has been gaining interest for its use as a green catalyst. However, microwave (MW) assisted enzymatic polymerizations which combine the benefits of both microwave heating and enzymatic catalysis is an area that is largely unexplored. This chapter focuses on the various microwave assisted organic and polymeric transformations including microwave assisted biocatalytic polymerizations that have been reported in literature in recent years.