Loading...
Detection and quantification of ketamine and clomiphene in complex matrices by LC and ESI-MSN
Lygrisse, Justin
Lygrisse, Justin
Citations
Altmetric:
Files
Loading...
Thesis
Adobe PDF, 826.69 KB
Authors
Other Names
Location
Time Period
Advisors
Original Date
Digitization Date
Issue Date
2009-05
Type
Thesis
Genre
Keywords
Subjects (LCSH)
Electronic dissertations
Citation
Abstract
The research presented here details the development of two separate methods for ESI-MS and LC. The first chapter gives an introduction to the first of the methods presented here, the detection of ketamine in alcoholic drinks. The second chapter gives a brief introduction into the relevance of developing a method for investigating clomiphene in biological samples. The third and fourth chapters outline the experimental parameters for the ketamine and clomiphene detection methods, respectively. Included are the parameters used for the mass spectrometer, liquid chromatography, and UV/Visible absorbance spectroscopy as well as the methods for extraction and sample work up. Chapter five outlines the development of a method for detecting and quantifying the date rape drug Ketamine HCl in alcoholic drink matrices. The sixth chapter outlines the development of LC and MS methods for detecting and quantifying clomiphene citrate in fetal calf serum and the initial results for the extraction and detection of clomiphene citrate in meconium. Chapters seven and eight present the conclusions for the ketamine and clomiphene studies, respectively, with directions for future studies.
Table of Contents
Description
Thesis (M.S.)--Wichita State University, College of Liberal Arts and Sciences, Dept. of Chemistry
Publisher
Wichita State University