Stem cell-based therapy for Parkinson's disease
Brice, Ryan Sai, Haneesha Vishwa Tran, Kimmy Garcia, Jade Ramirez, Edwyne Yao, Li
Brice, Ryan
Sai, Haneesha Vishwa
Tran, Kimmy
Garcia, Jade
Ramirez, Edwyne
Yao, Li
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Authors
Brice, Ryan
Sai, Haneesha Vishwa
Tran, Kimmy
Garcia, Jade
Ramirez, Edwyne
Yao, Li
Sai, Haneesha Vishwa
Tran, Kimmy
Garcia, Jade
Ramirez, Edwyne
Yao, Li
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Issue Date
2024-03-26
Type
Book chapter
Genre
Keywords
Differentiation,Dopamine,Parkinson's disease,Stem cell therapy,Transplantation
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Citation
Brice, R., Sai, H.V., Tran, K., Garcia, J., Ramirez, E., Yao, L. (2024). Stem Cell-Based Therapy for Parkinson’s Disease. In: Haider, K.H. (eds) Handbook of Stem Cell Applications. Springer, Singapore. https://doi.org/10.1007/978-981-99-7119-0_1
Abstract
Parkinson's disease (PD) is a primary neurodegenerative disease that can cause neuronal degeneration leading to disability. The continuing loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc) leads to progressive degeneration. Although considerable research has been conducted on this disease, the lost neuron function cannot be satisfactorily recovered. Current therapeutic methods are primarily focused on symptomatic treatment. It is a great challenge to prevent disease progression. The advancement of stem cell research has raised a promising alternative approach for treating PD. This chapter reviews the pathophysiological process of this disease and summarizes the concept and advances in stem cell research as a novel therapeutic option for PD. © Springer Nature Singapore Pte Ltd. 2024. All rights reserved.
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Publisher
Springer Nature
Journal
Handbook of Stem Cell Applications