Exercise-induced hypoalgesia following blood flow restricted exercise
Proppe, Christopher E. Rivera, P. M. Lubiak, S. M. Fukuda, D. H. Anderson, Abigail W. Mansy, H. A. Hill, E. C.
Proppe, Christopher E.
Rivera, P. M.
Lubiak, S. M.
Fukuda, D. H.
Anderson, Abigail W.
Mansy, H. A.
Hill, E. C.
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2025-03-06
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Keywords
Exercise-induced hypoalgesia,Pain management,Pain pressure threshold,Pain pressure tolerance
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Christopher E. Proppe, Paola M. Rivera, Sean M. Lubiak, David H. Fukuda, Abigail W. Anderson, Hansen A. Mansy, Ethan C. Hill, Exercise-induced hypoalgesia following blood flow restricted exercise, Physical Therapy in Sport, Volume 73, 2025, Pages 17-24, ISSN 1466-853X, https://doi.org/10.1016/j.ptsp.2025.02.011.
Abstract
Objectives: Assess the repeatability of exercise-induced hypoalgesia (EIH) following low-load resistance exercise with blood flow restriction (LL + BFR) and the magnitude of EIH following LL + BFR, high-load resistance exercise, and a control intervention 1-h after exercise. Design: Crossover design. Setting: University laboratory. Participants: 15 females, 15 males. Main outcome measures: Pain pressure threshold and tolerance of the rectus femoris, gastrocnemius, and biceps brachii pre-exercise and 0-, 15-, 30-, 45-, and 60-min post-exercise. Results: There was no significant (p = 0.211–0.741) difference in pain pressure threshold or tolerance between LL + BFR1 and LL + BFR2 suggesting that EIH following LL + BFR is repeatable. LL + BFR elicited a significant (p = 0.001–0.043) increase in local pain pressure threshold (1.57 ± 1.21–0.98 ± 1.48 Δkgf) and tolerance (1.98 ± 2.65–0.83 ± 2.15 Δkgf) up to 1-h post-exercise. High-load resistance exercise elicited a significant (p = 0.003–0.034) increase in pain pressure threshold 0-min post-exercise (1.69 ± 1.74 Δkgf) and tolerance 0- and 15-min post-exercise (2.31 ± 2.44 Δkgf; 0.56 ± 1.83 Δkgf, respectively) then returned to pre-exercise levels. LL + BFR elicited a significant (p = 0.025–0.046) increase in systemic pain pressure tolerance (0.77 ± 0.88 Δkgf) of the gastrocnemius as well as pain pressure threshold (0.53 ± 0.54 Δkgf) and tolerance (0.49 ± 1.02 Δkgf) of the biceps brachii, when collapsed across Time. Conclusions: LL + BFR may be a repeatable, effective pain management intervention that can produce prolonged EIH. © 2025
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Churchill Livingstone
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Physical Therapy in Sport
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1466853X