Loading...
Femtosecond laser Nanotexturing of drug-eluting stents
Bashir, Mahmood Al
Bashir, Mahmood Al
Citations
Altmetric:
Files
Loading...
Bashir_2017.pdf
Adobe PDF, 81.04 KB
Authors
Other Names
Location
Time Period
Advisors
Original Date
Digitization Date
Issue Date
2017-04-28
Type
Abstract
Genre
Keywords
Subjects (LCSH)
Citation
Bashir, Mahmood A. 2017. Femtosecond laser Nanotexturing of drug-eluting stents--In Proceedings: 13th Annual Symposium on Graduate Research and Scholarly Projects. Wichita, KS: Wichita State University, p.20
Abstract
Stents have been used for over a decade to treat coronary arteries affected by stenosis, a state where the arteries are narrowed by the deposition of plaque. But studies have found restenosis can hinder its purpose. Drug-eluting stents (DES) have a significant impact in treating restenosis. DES are embedded with drugs that are released over time after stent is placed within the artery, reducing the chance of plaque deposition around the stent. But DES risks the chance of increased thrombosis, which is a state when blood clots form around the stent because of a change in the blood flow profile. In our research we used femtosecond pulsed lasers to create Nano-textured patterns on a biomaterial, Tantalum and studied the structure. The 'peaks and valley' structure found under the microscope shows potentials to be used as a drug reservoir for the stents. Further studies are being conducted to test the fluid retention characteristics of the material, which can be a cost-effective solution to reduce or completely eliminate in-stent restenosis and thrombosis without the need of post-finishing operations. The interaction of bioelements with the metallic stents are also being tested to ensure the efficiency of the DES.
Table of Contents
Description
Presented to the 13th Annual Symposium on Graduate Research and Scholarly Projects (GRASP) held at the Rhatigan Student Center, Wichita State University, April 28, 2017.
Research completed in the Department of Mechanical Engineering, College of Engineering
Research completed in the Department of Mechanical Engineering, College of Engineering
Publisher
Wichita State University
Journal
Book Title
Series
GRASP
v. 13
v. 13