ItemFluorescence correlation spectroscopy: A quantitative study of pH responsive catanionic surfactant vesicles for drug delivery(Wichita State University. Graduate School, 2014-04-25) Wang, Zifan; Mishra, Archana; Pankratz, Daniel M.; Keomany, Stephanie; English, Douglas S.Catanionic surfactant vesicles form spontaneously from mixtures of single-tailed cationic and anionic surfactants. Catanionic vesicles can be formed from inexpensive components and are more stable than conventional liposomes formed from phospholipids. Catanionic vesicles are stable in solution, and in some instances, indefinitely. Hence they are promising materials for many of the applications currently fulfilled by liposomes including models of biological membranes, drug delivery and solubilizing agents. The surfactant n-tridecanoic (TDA) acid confers pH responsiveness to vesicles formed from mixtures of sodium dodecylbenzenesulfonate (SDBS) and cetyltrimethylammonium tosylate (CTAT) (TDA- SDBS/ CTAT). This ternary mixture is a function of pH and shows that anion-rich catanionic vesicles are promising pH-responsive carriers of cationic drug molecules. A new fluorescence correlation spectroscopy (FCS) method is promising as a measure of the binding constant of a cationic drug /dye molecule (doxorubicin) with three different vesicles formulations at the different pH. ItemBESS scores observed in real-time versus slow-motion video recording(Wichita State University. Graduate School, 2014-04-25) Stern, Danielle C.; Amick, Ryan Zackary; Jansen, Samantha D.; Patterson, Jeremy A.The Balance Error Scoring System (BESS) is a subjective clinical balance assessment frequently used by various healthcare providers. The test consists of three different stances (feet together, tandem, and single leg) that are each 20 seconds long. An administrator carefully observes and records the number of pre-defined balance or stability errors committed by the test subject. However, it is unclear if test administrators are able to observe all errors committed by the subject in real-time. 53 subjects were scored in person and recorded on video for slow-motion access while performing two series of BESS trials by an experienced BESS rater. No significant difference between means in overall total score in real-time or slow-motion (9.8 + 6.7 and 9.7 + 5.5 errors, respectively) were reported. Results of this study suggest that experienced BESS raters score balance errors consistently whether the test is in real-time or recorded and viewed in slow-motion. ItemThe effect of food supplementation on the survival of a small songbird, the Dark-eyed Junco (Junco hyemalis), using mark-recapture and radiotelemetry methods(Wichita State University. Graduate School, 2014-04-25) Spellmeyer, Andrew J.; Rogers, Christopher M.The North American Breeding Bird Survey indicates long-term decline of a medium-sized, granivorous sparrow, the Dark-eyed Junco (Junco hyemalis). Reduction in food availability due to habitat removal and degradation on the wintering grounds may be a source of decline. Access to predictable food stores affects the parameters of home range size and likely plays a role in predation risk. We measured the effect of food supplementation on the survival of individual juncos during a 70-day wintering period in four consecutive years using mark-recapture methods. Confirmation of bird locations via radiotelemetry suggests mark-recapture may lead to overestimation of mortality due to individual dispersal. However, a minimal estimate (correcting for dispersal) indicates food supplementation leads to a significant increase in overwinter survival. Populations with predictable seed stores likely spend less time searching for food and more time avoiding predators, thus increasing survival of supplemented birds. Increased overwinter survival may reverse annual decline. ItemComparison of maternal perceptions of perinatal care at a Midwest medical center with a free-standing birth center and a traditional labor, delivery, recovery unit(Wichita State University. Graduate School, 2014-04-25) Smith, Ginny; Morrison, BarbaraThe Baby Friendly Hospital (BFH) Initiative is a worldwide effort to improve breastfeeding rates through supportive hospital practices. The purpose of this project was to assess maternal perceptions of the perinatal care provided and confidence with newborn care at a Midwestern medical center as they initiated practice changes toward BFH designation. The COMFORTS scale was completed by 101 mothers prior to discharge after birth. Mean score on total scale was 208.07 plus/minus 25.33/240, indicating a high satisfaction with care, though first time mothers' satisfaction was lower (mean=200.72 plus/minus 27.30, t=-2.21, p=0.03). Mothers at the Birth Center perceived greater choice (t=2.46, p=0.02) and initiate early skin-to-skin care more frequently (FET=9.49, p=0.03) than mothers at the hospital unit. First time mothers were less confident with newborn care (t=-4.92, p=0.00) than mothers with an older child. Although satisfaction was high there is room for improvement as practice changes are being made. ItemUser performance, satisfaction, and preference of EMR access via desktop and tablet(Wichita State University. Graduate School, 2014-04-25) Teves, Jennifer P.; Fouquet, Sarah; Kennedy, Brandan; Chan, Y. Raymond; Riss, Robert; Chaparro, Barbara S.Providers are now accessing EMRs built for desktop platforms on mobile devices. Survey findings indicate that these EMR systems built for desktop platforms may not be accessed using mobile devices due to limited screen real-estate, increased scrolling, inaccurate interactions, and constant zooming to read information. The purpose of this study was to conduct a usability test to compare user performance and satisfaction of a commercial EMR on a desktop and an iPad. Participants were 16 attending physicians who performed seven EMR tasks on both the desktop and the iPad. Participants took longer to complete the EMR tasks and were less efficient on the iPad than on the desktop. They perceived higher workload and rated the tasks as more difficult on the iPad. These results indicate that use of an interface created for a desktop computer on a mobile device may result in a less efficient and less satisfying user experience.