Browsing by Type "Article"
Now showing items 1-20 of 3955
-
1,2,5-Thiadiazolidin-3-one 1,1 dioxide: a powerful scaffold for probing the S' subsites of (chymo)trypsin-like serine proteases
(Elsevier, 2001-01-01)The 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold (I) embodies a motif that allows it to dock to the active site of (chymo)trypsin-like proteases in a predictable and substrate-like fashion. Consequently, inhibitors ... -
1,2,5-Thiadiazolidin-3-one 1,1-dioxide-based heterocyclic sulfides are potent inhibitors of human tryptase
(Elsevier, 2005-04-01)We describe herein the design, synthesis, and in vitro biochemical evaluation of a series of potent, time-dependent inhibitors of the mast cell-derived serine protease tryptase. The inhibitors were readily obtained by ... -
158 Production of recombinant LH for use in tiger ( tigris altaica ) assisted reproduction: a preliminary report
(CSIRO, 2007-12-12)Genetically, porcine LH is the closest commercially available gonadotropin analog to tiger LH (93% homologous); however, its use may lead to possible autoimmune reactions, lessening ovarian responses in stimulated tigresses ... -
16PF profiles and four-point codes for clients seen in a private practice
(Wichita State University, Department of Psychology, 1986)The purpose of the study was to examine and describe the personality characteristics of 132 clients seen in a counseling psychology private practice. Ms and SDs for the sample indicated that these clients differed significantly ... -
19F nuclear magnetic resonance and crystallographic studies of 5-fluorotryptophan-labeled anthrax protective antigen and effects of the receptor on stability
(American Chemical Society, 2014-02-04)The anthrax protective antigen (PA) is an 83 kDa protein that is one of three protein components of the anthrax toxin, an AB toxin secreted by Bacillus anthracis. PA is capable of undergoing several structural changes, ... -
2, 2'-and 4, 4'-Cyanines are transporter-independent in vitro dopaminergic toxins with the specificity and mechanism of toxicity similar to MPP+
(Wiley Periodicals, Inc., 2015-11)Specific uptake through dopamine transporter followed by the inhibition of the mitochondrial complex-I have been accepted as the cause of the specific dopaminergic toxicity of 1-methyl-4-phenylpyridinium (MPP+). However, ... -
2-Fluoro-l-histidine
(International Union of Crystallography, 2010-01-01)The title compound, C(6)H(8)FN(3)O(2), an analog of histidine, shows a reduced side-chain pK(a) (ca 1). The title structure exhibits a shortening of the bond between the proximal ring N atom and the F-substituted ring C ... -
2-Stage stochastic programming approach for hub location problem under uncertainty: a case study of air network of Iran
(Elsevier B.V., 2015-08)In this paper 2-stage stochastic programming has been developed for formulating stochastic uncapacitated multiple allocation hub location problem. This problem is studied under three cases. The first, stochastic demand, ... -
20 things you didn't know about sex and heart disease
(Lippincott Williams & Wilkins, 2014-05) -
3-(Alkylthio)-N-hydroxysuccinimide derivatives: potent inhibitors of human leukocyte elastase
(Elsevier, 1993-08-07)A series of 3-(alkylthio)-N-hydroxysuccinimide derivatives was synthesized and their inhibitory activity towards human leukocyte elastase (HLE) was investigated. The interaction of the compounds having a 3-alkylthioether ... -
3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice
(NLM (Medline), 2020-08-19)Pathogenic coronaviruses are a major threat to global public health, as exemplified by severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and the newly emerged ... -
3S-fluoroproline as a probe to monitor proline isomerization during protein folding by 19F-NMR
(Royal Society of Chemistry, 2009-06-21)Variable-temperature inversion transfer NMR is used to determine the kinetic and thermodynamic parameters of cis-trans isomerization of N-Ac-(3R) and (3S)-fluoroproline-OMe. -
A 28-day case-study with the M.A.T.
(Western Institute of Multivariate Experimental Psychology, 1973)One subject completed the M.A.T. every day for a period of a month. In addition a detailed diary was kept for this period. Fluctuations in the scores of the M.A.T. variables were related to diary events. This procedure ... -
A brief note on second-order community satisfaction factors for two sub-communities in Istanbul, Turkey
(Wichita State University, Department of Psychology, 1990)First-order Community Satisfaction factors obtained for a sample of residents of Istanbul, Turkey, were subjected to second-order factor analysis; a solution with two oblique factors ("General Satisfaction" and ... -
A brief note on second-order community satisfaction factors for two sub-communities in Istanbul, Turkey
(Wichita State University. Department of Psychology, 1990)Fiest-order Community Satisfaction factors obtained for a sample of residents of Istanbul, Turkey, were subjected to second-order factor analysis; a solution with two oblique factors ("General Satisfaction" and ... -
A call for Social Work students in mine action
(Wichita State University, School of Social Work, 2016-02-19)For too many, physical and psychological trauma are the unfortunate consequences of living in post-conflict regions where landmines and explosive remnants of war (ERW) continue to litter roads, farmland, and other critical ... -
A canonical analysis of blood chemistry variables related to psychological measures of cancer patients
(Wichita State University, Department of Psychology, 1979)A canonical analysis was computed utilizing a battery of psychological variables (MMPI, IMAGE-CA, Locus of Control, FIRO-B and POMS), disease status, rehabilitation status, and blood chemistries (complete blood count, free ... -
A check on the 28 factor clinical analysis questionnaire structure on normal and pathological subjects
(Western Institute of Multivariate Experimental Psychology, 1973)Taking the widest currently possible array of items made up for various pathological behaviors, some five pioneer factorings have indicated 28 primary factors, 16 of which are the familiar normal personality factors of the ... -
A check on the factor-analytic structure of four O-A kit source traits, independence, evasiveness, realism and dissofrustance, found diagnostic of depression
(Wichita State University, Department of Psychology, 1981)Four source trait factors (U.I.19, 20, 25, and 30) that have been shown significantly to differentiate depressive from normals have been taken out of the O-A Kit and subjected to factor analysis, to check their patterns ... -
A check on the second-order factor structure of the high school personality questionnaire
(Wichita State University, Department of Psychology, 1976)A second order factor analysis of the HSPQ, using the promax method followed by blind had rotation to simple structure, was conducted. The results obtained for both males and females replicate well six factors previously reported.