Browsing by Subject "Bacillus anthracis/pathogenicity"

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    • Evidence that histidine protonation of receptor-bound anthrax protective antigen is a trigger for pore formation 

      Wimalasena, D. Shyamali; Janowiak, Blythe E.; Lovell, Scott; Miyagi, Masaru; Sun, Jianjun; Zhou, Haiying; Hajduch, Jan; Pooput, Chaya; Kirk, Kenneth L.; Battaile, Kevin P.; Bann, James G. (American Chemical Society, 2010-08-24)
      The protective antigen (PA) component of the anthrax toxin forms pores within the low pH environment of host endosomes through mechanisms that are poorly understood. It has been proposed that pore formation is dependent ...