Groutas, William C.; Schechter, Norman M.; He, Shu; Yu, Hongyi; Huang, Peng; Tu, Juan
(Elsevier, 1999-08-02)
A series of compounds that utilize the 1,2,5-thiadiazolidin-3-one 1,1 dioxide scaffold was synthesized and shown to be highly effective inhibitors of recombinant human skin chymase.