Preparation of 2,2’‐bipyrazine and 5,5’‐dimethyl‐2,2’‐bipyrazine

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dc.contributor.author	Liyanage, Pithma
dc.date.accessioned	2012-09-19T21:09:14Z
dc.date.available	2012-09-19T21:09:14Z
dc.date.issued	2008-04-25
dc.identifier.uri	http://webs.wichita.edu/?u=urcaf&p=/PosterabstractPithmaJithLiyanage/
dc.identifier.uri	http://hdl.handle.net/10057/5291
dc.description	First place winner of poster presentations in the Natural Science section at the 8th Annual Undergraduate Research and Creative Activity Forum (URCAF) held at the Eugene Hughes Metropolitan Complex , Wichita State University, April 25, 2008	en_US
dc.description.abstract	Procedures to maximize the product yields in the preparation of the title compounds were investigated. The general preparative procedures for 2,2’‐bipyrazine (bpz) and 5,5’‐dimethyl‐2,2’‐bipyrazine (Me2bpz)was as follows: Copper(II) salts of 2‐pyrazine carboxylic acid (pzCOOH) and 5‐methyl‐2‐pyrazinecarboxylic acid (MepzCOOH) were obtained by reacting copper(II) chloride in water with a stoichiometric quantity of the appropriate acid to give Cu(pzCOO)2 and Cu(MepzCOO)2. The blue solid was removed by filtration, dried in a vacuum oven at 60 °C and then cooled to room temperature. It was then placed in a pyrolysis apparatus and the solid was heated to 300 °C. The products were separated from the remaining solid by a stream of argon gas and deposited on the walls of a condenser. The deposit was then removed and dissolved in acetone. Upon concentration of the material by evaporation of the acetone, it precipitated and was removed by filtration. It was then purified by repeating the process of dissolution in acetone, concentrating it by evaporation of the acetone and collecting the precipitate. The maximum yield of bpz was ~20% and ~2% for Me2bpz. The compounds melted sharply at 167 °C and 138 °C, respectively. Variations in preparative procedures and pyrolysis techniques were examined and product yields were determined. Some of the variations were to add elemental copper to the solid undergoing pyrolysis, changing the stoichiometry of the acid added to the reaction mixture and altering the design of the pyrolysis apparatus.	en_US
dc.description.sponsorship	Faculty Sponsor: D Paul Rillema; Office of Research Administration, Fairmount College of Liberal Arts and Sciences, College of Education, College of Engineering, College of Fine Arts, University Libraries, Emory Lindquist Honors Program	en_US
dc.language.iso	en_US	en_US
dc.publisher	Wichita State University	en_US
dc.relation.ispartofseries	URCAF;
dc.relation.ispartofseries	v.8;
dc.title	Preparation of 2,2’‐bipyrazine and 5,5’‐dimethyl‐2,2’‐bipyrazine	en_US
dc.type	Abstract	en_US