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dc.contributor.authorZhao, Yunpeng
dc.contributor.authorZhang, Aijun
dc.contributor.authorDu, Hongxia
dc.contributor.authorGuo, Shuya
dc.contributor.authorNing, Bin
dc.contributor.authorYang, Shang-You
dc.date.accessioned2012-04-27T18:38:48Z
dc.date.available2012-04-27T18:38:48Z
dc.date.issued2012-04
dc.identifier.citationZhao, Yunpeng, Aijun Zhang, Hongxia Du, Shuya Guo, Bin Ning, and Shangyou Yang. 2012. "Tolerogenic dendritic cells and rheumatoid arthritis: current status and perspectives". Rheumatology International. 32 (4): 837-844.en_US
dc.identifier.issn0172-8172
dc.identifier.otherWOS: 000302145800001
dc.identifier.urihttp://hdl.handle.net/10057/5088
dc.identifier.urihttp://dx.doi.org/10.1007/s00296-011-2133-2
dc.descriptionClick on the DOI link below to access the review article (may not be free).en_US
dc.description.abstractRheumatoid arthritis (RA) is a chronic autoimmune disease characterized by the influxation of synovia and synovial compartments with immune cells including dendritic cells (DCs). DCs that induce autoimmune tolerance are called tolerogenic DCs (tolDCs). As a promising immunotherapeutic strategy for RA, tolDCs have received increasing attention. In this review, we first introduce the significant role of tolDCs in autoimmune regulation and then describe the manipulation strategies to generate tolDCs; next, we summarize recent progress in the experimental application of tolDCs for RA therapy, and finally we discuss the perspectives of tolerogenic vaccination for the treatment for RA in clinic.en_US
dc.language.isoen_USen_US
dc.publisherSpringeren_US
dc.relation.ispartofseriesRheumatology International;2012, v.32, no.4
dc.subjectRheumatoid arthritisen_US
dc.subjectDendritic cellsen_US
dc.subjectTolerogenic DCsen_US
dc.subjectTregsen_US
dc.subjectAutoimmuneen_US
dc.subject.classificationRHEUMATOLOGY
dc.titleTolerogenic dendritic cells and rheumatoid arthritis: current status and perspectivesen_US
dc.typeArticleen_US
dc.description.versionPeer reviewed
dc.rights.holderCopyright by Springer-Verlag 2011


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