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Effect of beta-hydroxy beta-methylbutyrate on the onset of blood lactate accumulation and V(O)(2) peak in endurance-trained cyclists

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dc.contributor Wichita State University. Department of Human Performance Studies en_US
dc.contributor.author Vukovich, Matthew D. en_US
dc.contributor.author Dreifort, Geri D. en_US
dc.date.accessioned 2012-03-30T19:24:00Z
dc.date.available 2012-03-30T19:24:00Z
dc.date.issued 2001-11 en_US
dc.identifier 11726262 en_US
dc.identifier 9415084 en_US
dc.identifier.citation Journal of strength and conditioning research / National Strength & Conditioning Association. 2001 Nov; 15(4): 491-7. en_US
dc.identifier.issn 1064-8011 en_US
dc.identifier.uri http://hdl.handle.net/10057/5016
dc.description The full text of this article is not available in SOAR. en_US
dc.description.abstract The purpose of this study was to determine the effect of beta-hydroxy beta-methylbutyrate (HMB) supplementation on maximal oxygen consumption (.V(O)(2)peak) and the onset of blood lactate accumulation (OBLA) in endurance-trained cyclists. Eight cyclists randomly (double blind) completed 3 2-week supplementation periods (HMB, 3g.day(-1); leucine [LEU], 3g.day(-1); placebo [CON], 3g.day(-1)) followed by a 2-week washout period. Testing consisted of a graded cycle ergometry test to measure .V(O)(2)peak and OBLA, the .V(O)(2) at 2 mM blood lactate. .V(O)(2)peak was unaffected by HMB (4.0 +/- 1.4%), LEU (-1.9 +/- 1.3%), and CON (-2.6 +/- 2.6%). HMB resulted in a greater time to reach .V(O)(2)peak, whereas LEU and CON did not affect this time (HMB, 3.6 +/- 1.5 min, LEU, -1.2 +/- 1.5 min; CON, -3.6 +/- 3.5 min). Lactate accumulation peak was unaffected by supplementation (HMB, 8.1 +/- 1.1 mM; LEU, 6.2 +/- 0.8 mM; CON, 7.5 +/- 1.3 mM). OBLA increased with HMB (9.1 +/- 2.4%) and LEU (2.1 +/- 1.5%), but not in the CON trial (0.75 +/- 2.1%). Blood glucose was significantly greater during the HMB trial compared with the LEU trial. It is concluded that HMB supplementation may have positive affects on performance by increasing the onset of blood lactate accumulation; however, the mechanism is unknown. en_US
dc.format.extent 491-7 en_US
dc.language.iso eng en_US
dc.publisher Lippincott Williams & Wilkins en_US
dc.relation.ispartofseries Journal of Strength and Conditioning Research / National Strength & Conditioning Association en_US
dc.relation.ispartofseries J Strength Cond Res en_US
dc.source NLM en_US
dc.subject Clinical Trial en_US
dc.subject Comparative Study en_US
dc.subject Randomized Controlled Trial en_US
dc.subject Research Support, Non-U.S. Gov't en_US
dc.subject.mesh Adult en_US
dc.subject.mesh Anaerobic Threshold/drug effects en_US
dc.subject.mesh Analysis of Variance en_US
dc.subject.mesh Bicycling/physiology en_US
dc.subject.mesh Blood Glucose/drug effects en_US
dc.subject.mesh Cross-Over Studies en_US
dc.subject.mesh Dietary Supplements en_US
dc.subject.mesh Double-Blind Method en_US
dc.subject.mesh Exercise/physiology en_US
dc.subject.mesh Hematocrit en_US
dc.subject.mesh Hemoglobins/drug effects en_US
dc.subject.mesh Humans en_US
dc.subject.mesh Lactates/blood en_US
dc.subject.mesh Leucine/administration & dosage en_US
dc.subject.mesh Male en_US
dc.subject.mesh Oxygen Consumption/drug effects en_US
dc.subject.mesh Physical Education and Training/methods en_US
dc.subject.mesh Physical Endurance/drug effects en_US
dc.subject.mesh Time Factors en_US
dc.subject.mesh Valerates/blood en_US
dc.subject.mesh Valerates/pharmacology en_US
dc.title Effect of beta-hydroxy beta-methylbutyrate on the onset of blood lactate accumulation and V(O)(2) peak in endurance-trained cyclists en_US
dc.type Article en_US
dc.coverage.spacial United States en_US
dc.description.version peer reviewed en_US
dc.rights.holder Copyright © 2001 National Strength and Conditioning Association en_US

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