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Nanoporous impedemetric biosensor for detection of trace atrazine from water samples

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dc.contributor.author Pichetsurnthorn, Pie
dc.contributor.author Vattipalli, Krishna
dc.contributor.author Prasad, Shalini
dc.date.accessioned 2012-03-22T18:27:56Z
dc.date.available 2012-03-22T18:27:56Z
dc.date.issued 2012-02-15
dc.identifier.citation Pichetsurnthorn, P., K. Vattipalli, and S. Prasad. 2012. "Nanoporous impedemetric biosensor for detection of trace atrazine from water samples". Biosensors and Bioelectronics. 32 (1): 155-162. en_US
dc.identifier.issn 0956-5663
dc.identifier.issn 1873-4235
dc.identifier.other WOS: 000301011100022
dc.identifier.uri http://hdl.handle.net/10057/4921
dc.identifier.uri http://dx.doi.org/10.1016/j.bios.2011.11.055
dc.description Click on the DOI link below to access the article (may not be free). en_US
dc.description.abstract Trace contamination of ground water sources has been a problem ever since the introduction of high-soil-mobility pesticides, one such example is atrazine. In this paper we present a novel nanoporous portable bio-sensing device that can identify trace contamination of atrazine through a label-free assay. We have designed a pesticide sensor comprising of a nanoporous alumina membrane integrated with printed circuit board platform. Nanoporous alumina in the biosensor device generates a high density array of nanoscale confined spaces. By leveraging the size based immobilization of atrazine small molecules we have designed electrochemical impedance spectroscopy based biosensor to detect trace amounts of atrazine. We have calibrated the sensor using phosphate buffered saline and demonstrated trace detection from river and bottled drinking water samples. The limit of detection in all the three cases was in the femtogram/mL (fg/mL) (parts-per-trillion) regime with a dynamic range of detection spanning from 10 fg/mL to 1 ng/mL (0.01 ppt to 1 ppm). The selectivity of the device was tested using a competing pesticide; malathion and selectivity in detection was observed in the fg/mL regime in all the three cases. en_US
dc.language.iso en_US en_US
dc.publisher Elsevier en_US
dc.relation.ispartofseries Biosensors and Bioelectronics;2012:, v.32, no.1
dc.subject Trace atrazine detection en_US
dc.subject River water en_US
dc.subject Drinking water en_US
dc.subject Electrochemical impedance spectroscopy en_US
dc.subject Nanoporous alumina en_US
dc.subject Label-free detection en_US
dc.subject.classification BIOPHYSICS
dc.subject.classification BIOTECHNOLOGY & APPLIED MICROBIOLOGY
dc.subject.classification CHEMISTRY
dc.subject.classification ELECTROCHEMISTRY
dc.subject.classification SCIENCE & TECHNOLOGY
dc.title Nanoporous impedemetric biosensor for detection of trace atrazine from water samples en_US
dc.type Article en_US
dc.description.version Peer reviewed
dc.rights.holder Copyright © 2012, Elsevier

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