Design, synthesis and biological evaluation of succinimide derivatives as potential mechanism-based inhibitors of human leukocyte elastase, cathepsin G and proteinase 3
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Design, synthesis and biological evaluation of succinimide derivatives as potential mechanism-based inhibitors of human leukocyte elastase, cathepsin G and proteinase 3
Groutas, William C.; Brubaker, Michael J.; Chong, Lee S.; Venkataraman, Radhika; Huang, He; Epp, Jeffrey B.; Kuang, Rongze; Hoidal, John R.
Structure-activity relationship study and in vitro biochemical studies with human leukocyte elastase, cathepsin G and proteinase 3 were conducted using a series of succinimide derivatives.
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