SOAR Home
→
Liberal Arts and Sciences
→
Chemistry
→
CHEM Faculty Scholarship
→
CHEM Faculty Publications
→
Browsing CHEM Faculty Publications by Title

Browsing CHEM Faculty Publications by Title

Now showing items 69-88 of 253

Effect of 2-fluorohistidine labeling of the anthrax protective antigen on stability, pore formation, and translocation

Wimalasena, D. Shyamali; Cramer, John C.; Janowiak, Blythe E.; Juris, Stephen J.; Melnyk, Roman A.; Anderson, David E.; Kirk, Kenneth L.; Collier, R. John; Bann, James G. (American Chemical Society, 2007-12-25)

The action of anthrax toxin relies in part upon the ability of the protective antigen (PA) moiety to form a heptameric pore in the endosomal membrane, providing a portal for entry of the enzymic moieties of the toxin into ...
Effect of axial ligation or pi-pi-type interactions on photochemical charge stabilization in "two-point" bound supramolecular porphyrin-fullerene conjugates

D'Souza, Francis; Chitta, Raghu; Gadde, Suresh; Zandler, Melvin E.; McCarty, Amy L.; Sandanayaka, Atula S. D.; Araki, Yasuyaki; Ito, Osamu (John Wiley and Sons, 2005-07-18)

Two types of structurally well-defined, self-assembled zinc porphyrin-fullerene conjugates were formed by "two-point" binding strategies to probe the effect of axial ligation or pi-pi-type interactions on the photochemical ...
Effects of structure on inhibitory activity in a series of mechanism-based inhibitors of human neutrophil elastase

Dou, Dengfeng; He, Guijia; Kuang, Rongze; Fu, Qingfong; Venkataraman, Radhika; Groutas, William C. (Elsevier, 2010-09-15)

A structurally-diverse series of carboxylate derivatives based on the 1,2,5-thiadiazolidin-one 1,1 dioxide scaffold were synthesized and used to probe the S' subsites of human neutrophil elastase (HNE) and neutrophil ...
Efficient inhibition of human leukocyte elastase and cathepsin G by saccharin derivatives

Groutas, William C.; Houser-Archield, Nadene; Chong, Lee S.; Venkataraman, Radhika; Epp, Jeffrey B.; Huang, He; McClenahan, Jerald J. (American Chemical Society, 1993-10-15)

A series of saccharin derivatives I has been synthesized and evaluated for their inhibitory activity toward human leukocyte elastase and cathepsin G. Most of the compounds were found to be efficient and time-dependent ...
Electrochemical, spectral, and computational studies of metalloporphyrin dimers formed by cation complexation of crown ether cavities

Chitta, Raghu; Rogers, Lisa M.; Wanklyn, Amber; Karr, Paul A.; Kahol, Pawan K.; Zandler, Melvin E.; D'Souza, Francis (American Chemical Society, 2004-11-01)

The effect on the electrochemical oxidation and reduction potentials of 5,10,15,20-tetrakis(benzo-15-crown-5)porphyrin (TCP) and its metal derivatives (MTCP; M = Mg(II), VO(IV), Co(II), Ni(II), Cu(II), Zn(II), Pd(II), ...
Electrochemistry and spectral characterization of oxidized and reduced (TPPBr(x)())FeCl where TPPBr(x)() is the dianion of beta-brominated-pyrrole tetraphenylporphyrin and x varies from 0 to 8

Tagliatesta, Pietro; Li, Jun; Autret, Marie; Van Caemelbecke, Eric; Villard, Anne; D'Souza, Francis; Kadish, Karl M. (American Chemical Society, 1996-09-11)

The electrochemistry and spectroelectrochemistry of (TPPBr(x)())FeCl (TPPBr(x)() is the dianion of beta-brominated-pyrrole tetraphenylporphyrin and x = 0-8) were examined in PhCN containing tetra-n-butylammonium perchlorate ...
Electronic energy harvesting multi BODIPY-zinc porphyrin dyads accommodating fullerene as photosynthetic composite of antenna-reaction center

Maligaspe, Eranda; Kumpulainen, Tatu; Subbaiyan, Navaneetha K.; Zandler, Melvin E.; Lemmetyinen, Helge; Tkachenko, Nikolai V.; D'Souza, Francis (Royal Society of Chemistry, 2010-07-21)

Efficient electronic energy transfer (EET) in the newly synthesized dyads comprised of zinc porphyrin covalently linked to one, two or four numbers of boron dipyrrin (BDP) entities is investigated. Both steady-state and ...
Electronic, Spectral, and Electrochemical Properties of (TPPBr(x)())Zn Where TPPBr(x)() Is the Dianion of beta-Brominated-Pyrrole Tetraphenylporphyrin and x Varies from 0 to 8

D'Souza, Francis; Zandler, Melvin E.; Tagliatesta, Pietro; Ou, Zhongping; Shao, Jianguo; Van Caemelbecke, Eric; Kadish, Karl M. (American Chemical Society, 1998-09-07)

The electronic, spectral, and electrochemical characterization of (meso-tetraphenylporphyrinato)zinc(II) complexes bearing between 0 and 8 bromo substituents at the beta-pyrrole positions is reported. The investigated ...
Electron transfer dissociation of dipositive uranyl and plutonyl coordination complexes

Rios, Daniel; Rutkowski, Philip X.; Shuh, David K.; Bray, Travis H.; Gibson, John K.; Van Stipdonk, Michael J. (John Wiley and Sons, 2011-12)

Reported here is a comparison of electron transfer dissociation (ETD) and collision-induced dissociation (CID) of solvent-coordinated dipositive uranyl and plutonyl ions generated by electrospray ionization. Fundamental ...
Elucidation of the collision induced dissociation pathways of water and alcohol coordinated complexes containing the uranyl cation

Van Stipdonk, Michael J.; Anbalagan, Victor; Chien, Winnie; Gresham, Garold L.; Groenewold, Gary S.; Hanna, Dorothy A. (Springer, 2003-11-01)

Multiple-stage tandem mass spectrometry was used to characterize the dissociation pathways for complexes composed of (1) the uranyl ion, (2) nitrate or hydroxide, and (3) water or alcohol. The complex ions were derived ...
Enantioselective inhibition of human leukocyte elastase

Groutas, William C.; Brubaker, Michael J.; Venkataraman, Radhika; Stanga, Michael A. (Elsevier, 1992-08-15)

(RS)-Diethyl-2-benzyl-succinate was resolved using alpha-chymotrypsin. The two enantiomers were then elaborated to yield (S)-(+) and (R)-(-)-3-benzyl-N-[(methyl-sulfonyl)oxy]succinimide and the inhibitory activity of the ...
Energy transfer followed by electron transfer in a supramolecular triad composed of boron dipyrrin, zinc porphyrin, and fullerene: a model for the photosynthetic antenna-reaction center complex

D'Souza, Francis; Smith, Phillip M.; Zandler, Melvin E.; McCarty, Amy L.; Itou, Mitsunari; Araki, Yasuyaki; Ito, Osamu (American Chemical Society, 2004-06-30)

The first example of a working model of the photosynthetic antenna-reaction center complex, constructed via self-assembled supramolecular methodology, is reported. For this, a supramolecular triad is assembled by axially ...
Enhanced photocurrents via redox modulation by fluoride binding to oxoporphyrinogen in a zinc porphyrin-oxoporphyrinogen surface modified TiO2 supramolecular solar cell

Subbaiyan, Navaneetha K.; Hill, Jonathan P.; Ariga, Katsuhiko; Fukuzumi, Shunichi; D'Souza, Francis (Royal Society of Chemistry, 2011-06-07)

A novel approach for improving photocurrent in a supramolecular solar cell, composed of zinc porphyrin-oxoporphyrinogen (ZnP-OxP) surface-modified TiO(2), by redox tuning through fluoride anion binding to the redox active ...
Evidence for a hydrogen abstraction mechanism in P450-catalyzed N-dealkylations

Bhakta, Mehul N.; Hollenberg, Paul F.; Wimalasena, Kandatege (Royal Society of Chemistry, 2005-01-14)

The experimental evidence presented in this manuscript suggest against the widely accepted single electron/proton transfer mechanism for P450 catalyzed N-dealkylations and provides strong support for a hydrogen atom ...
Evidence that histidine protonation of receptor-bound anthrax protective antigen is a trigger for pore formation

Wimalasena, D. Shyamali; Janowiak, Blythe E.; Lovell, Scott; Miyagi, Masaru; Sun, Jianjun; Zhou, Haiying; Hajduch, Jan; Pooput, Chaya; Kirk, Kenneth L.; Battaile, Kevin P.; Bann, James G. (American Chemical Society, 2010-08-24)

The protective antigen (PA) component of the anthrax toxin forms pores within the low pH environment of host endosomes through mechanisms that are poorly understood. It has been proposed that pore formation is dependent ...
Excited-state proton transfer in complexes of poly(methacrylic acid) with dodecyltrimethylammonium chloride

Kombarova, Svetlana V.; Il'ichev, Yuri V. (American Chemical Society, 2004-07-20)

Proton-transfer reactions in aqueous solutions of poly(methacrylic acid) (PMA) were studied using a fluorescent probe and Fourier transform infrared (FTIR) spectroscopy. Protolytic photodissociation of 1-hydroxypyrene (HP) ...
Face-to-face pacman-type porphyrin-fullerene dyads: design, synthesis, charge-transfer interactions, and photophysical studies

D'Souza, Francis; Maligaspe, Eranda; Karr, Paul A.; Schumacher, Amy Lea; El Ojaimi, Maya; Gros, Claude P.; Barbe, Jean-Michel; Ohkubo, Kei; Fukuzumi, Shunichi (John Wiley and Sons, 2008-01-01)

Pacman-type face-to-face zinc-porphyrin-fullerene dyads have been newly synthesized and studied. Owing to the close proximity of the donor and acceptor entities, strong pi-pi intramolecular interactions between the porphyrin ...
Fluorophore(s) appended fullerene dyads and triads for probing photoinduced energy transfer: syntheses, electronic structure, and fluorescence studies

Deviprasad, Gollapalli R.; Smith, Phillip M.; Zandler, Melvin E.; Rogers, Lisa M.; D'Souza, Francis (Springer, 2006-01-01)

Fullerene, C(60) was functionalized to possess one or two fluorophore entities. The fluorophore-fullerene dyads thus synthesized contain either a naphthalene, pyrene, or fluorene entity while the triads contain either a ...
Forbidden Electronic Transitions between the Singlet Ground State and the Triplet Excited State of Pt(II) Complexes

Zheng, Greg Y.; Rillema, D. Paul; DePriest, Jeff; Woods, Clifton (American Chemical Society, 1998-07-13)

Direct access to the triplet emitting state from the ground state is observed for Pt(II) complexes containing heterocyclic (CwedgeC', CwedgeN, NwedgeN') and bis(diphenylphosphino)alkane (PwedgeP') ligands. Extinction ...
Formation of [b3 - 1 + cat]+ ions from metal-cationized tetrapeptides containing beta-alanine, gamma-aminobutyric acid or epsilon-aminocaproic acid residues

Osburn, Sandra M.; Ochola, Sila O.; Talaty, Erach R.; Van Stipdonk, Michael J. (John Wiley and Sons, 2008-11-01)

The presence and position of a single beta-alanine (betaA), gamma-aminobutyric acid (gammaABu) or epsilon-aminocaproic acid (Cap) residue has been shown to have a significant influence on the formation of b(n)+ and y(n)+ ...