Now showing items 1-2 of 2

  • Cardiac hormones are c-Jun-N-Terminal Kinase 2-inhibiting peptides 

    Lane, Meghan L.; Santana, Omar; Frost, Chelsea D.; Nguyen, Jennifer; Guerrero, Jennifer; Skelton, William P.; Skelton, Michelle; Vesely, David L. (International Institute of Anticancer Research, 2012-03)
    Background: Four cardiac peptide hormones, namely vessel dilator, long-acting natriuretic peptide (LANP), kaliuretic peptide, and atrial natriuretic peptide (ANP) have anticancer effects. Materials and Methods: The effects ...
  • Potent selective inhibition of STAT 3 versus STAT 1 by cardiac hormones. 

    Lane, Meghan L.; Frost, Chelsea D.; Nguyen, Jennifer; Skelton, William P.; Skelton, Michelle; Vesely, David L. (Springer, 2012-12)
    Signal transducers and activators of transcription (STATs) are the final "switches" that activate gene expression patterns that lead to human malignancy. Extracellular signal-regulated kinases (ERK 1/2) activate STAT 3; ...