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Abnormal expression of genes associated with development and inflammation in the heart of mouse maternal phenylketonuria offspring

Matalon, R.; Surendran, S.; McDonald, J. David; Okorodudu, A. O.; Tyring, S. K.; Michals-Matalon, K.; Harris, P. (PubMed, 2005)

This study describes gene expression in the fetus hearts obtained from mouse model for phenylketonuria. These hearts have cardiovascular disease (CVD). Therefore genes involved in CVD were examined. Several genes associated ...
Adenosine modulation of dynorphin B release by hippocampal synaptosomes

Loewen, Jonathan J.; Peters, Ralph I.; Terrian, David M. (ElsevierElsevier BV, 1992-04-17)

A rat hippocampal preparation enriched in mossy fiber synaptosomes was employed in an attempt to expose any relationship between endogenous adenosine and the release of dynorphin B-like immunoreactivity (DynB-LI). Presumptive ...
All-or-none N-glycosylation in primate follicle-stimulating hormone beta-subunits

Bousfield, George R.; Butnev, Vladimir Y.; Walton, Wendy J.; Nguyen, Van T.; Huneidi, Jennifer; Singh, Vinod; Kolli, V. S. Kumar; Harvey, David J.; Rance, Naomi E. (Elsevier Ireland Ltd, 2007-01-02)

Human FSH exists as two major glycoforms designated, tetra-glycosylated and di-glycosylated hFSH. The former possesses both alpha- and beta-subunit carbohydrates while the latter possesses only alpha-subunit carbohydrate. ...
Alternative method for isolation of double-stranded template for DNA sequencing

Sadiev, Sagypash; Taylor, Alan (Informa Healthcare, 1996-08)

The increased use of plasmid DNAs in recombinant DNA technology, coupled with the growing popularity of double-stranded DNA sequencing, necessitates the development of rapid, inexpensive and efficient procedures ...
Anaerobically induced production of hybrid monokaryons by heterokaryons of Candida albicans

Sarachek, Alvin (Springer Netherlands, 1989-01)

During aerobic replication, balanced heterokaryons (hets) of Candida albicans produced by fusing protoplasts of complementing auxotrophic strains characteristically segregate low frequencies of prototrophic monokaryons ...
Analysis of multiple pesticides in urban storm water using solid-phase extraction

Belden, J. B.; Hofelt, C. S.; Lydy, Michael J. (Springer New York, 2000-01)

An analytical method was developed using C(18) solid-phase extraction and gas chromatography-nitrogen phosphorus detection (GC-NPD) to determine the presence and quantity of 12 contemporary pesticides in storm water runoff ...
The anti-cancer agent distamycin A displaces essential transcription factors and selectively inhibits myogenic differentiation

Taylor, Alan; Webster, Keith A.; Gustafson, Thomas A.; Kedes, Larry (Springer New York, 1997-04)

The anticancer drug, distamycin A, alters DNA conformation by binding to A/T-rich domains. We propose that binding of the drug to DNA alters transcription factor interactions and that this may alter genetic regulation. We ...
Archaeal diversity at the great salt plains of Oklahoma described by cultivation and molecular analyses

Caton, Todd M.; Santos-Caton, Ingrid R.; Witte, Lisa R.; Schneegurt, Mark A. (Springer New York, 2009-10)

The Great Salt Plains of Oklahoma is a natural inland terrestrial hypersaline environment that forms evaporite crusts of mainly NaCl. Previous work described the bacterial community through the characterization of 105 ...
Assessing the impact of triazine herbicides on organophosphate insecticide toxicity to the earthworm Eisenia fetida

Lydy, Michael J.; Linck, S. L. (Springer New York, 2003-10)

A standard Organization for Economic Cooperation and Development (OECD) filter paper test was used to assess the acute toxicity of chlorpyrifos, atrazine, cyanazine, and simazine to the earthworm Eisenia fetida. Acute ...
Assessment of water quality in Wichita, Kansas, using an index of biotic integrity and analysis of bed sediment and fish tissue for organochlorine insecticides

Eaton, H. J.; Lydy, Michael J. (Springer New York, 2000-11)

This study investigated water quality of the Arkansas River and its tributaries in the Wichita, Kansas, area. Water quality assessment included an evaluation of urban versus agricultural areas using a twofold approach: (1) ...
An assessment of water quality, physical habitat, and biological integrity of an urban stream in Wichita, Kansas, prior to restoration improvements (phase I)

Davis, Nate M.; Weaver, V.; Parks, K.; Lydy, Michael J. (Springer New York, 2003-04)

Urban development alters the natural hydrological conditions of many streams and rivers often resulting in the degradation of water quality, physical habitat, and biotic integrity of lotic systems. Restoration projects ...
Bacterial growth at the high concentrations of magnesium sulfate found in martian soils

Crisler, James D.; Newville, T. M.; Chen, F.; Clark, B. C.; Schneegurt, Mark A. (Mary Ann Liebert, 2012-02)

The martian surface environment exhibits extremes of salinity, temperature, desiccation, and radiation that would make it difficult for terrestrial microbes to survive. Recent evidence suggests that martian soils contain ...
Biochemical defect of the hph-1 mouse mutant is a deficiency in GTP-cyclohydrolase activity

McDonald, J. David; Cotton, R. G.; Jennings, I.; Ledley, F. D.; Woo, S. L.; Bode, V. C. (PubMed, 1988-02)

A hyperphenylalaninemic mouse mutant, hph-1, has been identified in the progeny of mice treated with the mutagen ethylnitrosourea. Phenylalanine hydroxylase activity levels in mutant liver lysates are reduced relative to ...
Biological observations and a new state record of Paracotalpa granicollis Haldeman (Coleoptera: Scarabaeidae: Rutelinae) in New Mexico

Kaufman, Paul; Jameson, Mary Liz (The Coleopterists Society, 2009)

Specimens of Paracotalpa granicollis Haldeman (Coleoptera: Scarabaeidae: Rutelinae) collected in northwestern New Mexico represent a new state record for the species. Individuals (males only) were observed in association ...
Biomass byproducts for the remediation of wastewaters contaminated with toxic metals

Schneegurt, Mark A.; Jain, Jain C.; Menicucci, John A.; Brown, Sarah A.; Kemner, Kenneth M.; Garofalo, David F.; Quallick, Matthew R.; Neal, Clive R.; Kulpa, Charles F. (American Chemical Society, 2001-09-15)

Pollution of the environment with toxic metals is widespread and often involves large volumes of wastewater. Remediation strategies must be designed to support high throughput while keeping costs to a minimum. Biosorption ...
Bolboceras Kirby, 1819 (July) (Insecta, Coleoptera): proposed precedence over Odonteus Samouelle, 1819 (June)

Jameson, Mary Liz; Howden, H.F. (International Trust for Zoological Nomenclature, 2002-12)

The purpose of this application, under Articles 23.9.3 and 8 1.2.3 of the Code, is to conserve the generic name Bolboceras Kirby, 1819 for a group of scarab beetles (family GEOTRUPIDAE) by giving it conditional precedence ...
Carbohydrate analysis of glycoprotein hormones

Bousfield, George R.; Baker, Vanda L.; Gotschall, R. Russell; Butnev, Vladimir Y. (Academic Press, 2000-05)

Complete carbohydrate composition analysis of glycoprotein hormones, their subunits, and oligosaccharides isolated from individual glycosylation sites can be accomplished using high-pH anion-exchange chromatography combined ...
Carbon substrate utilization, antibiotic sensitivity, and numerical taxonomy of bacterial isolates from the Great Salt Plains of Oklahoma

Litzner, Brandon R.; Caton, Todd M.; Schneegurt, Mark A. (Springer, 2006-05)

The current work extends the phenotypic characterization of a bacterial culture collection from the Great Salt Plains of Oklahoma. This barren expanse of mud flats is typically crusted with thalassohaline salt evaporites. ...
Carcinogenic effects in a phenylketonuria mouse model

Sidell, Neil; Hao, Lijuan; Pasquali, Marzia; McDonald, J. David (PubMed, 2009-01-27)

Phenylketonuria (PKU) is a metabolic disorder caused by impaired phenylalanine hydroxylase (PAH). This condition results in hyperphenylalaninemia and elevated levels of abnormal phenylalanine metabolites, among which is ...
Cardiac hormones are c-Jun-N-Terminal Kinase 2-inhibiting peptides

Lane, Meghan L.; Santana, Omar; Frost, Chelsea D.; Nguyen, Jennifer; Guerrero, Jennifer; Skelton, William P.; Skelton, Michelle; Vesely, David L. (International Institute of Anticancer Research, 2012-03)

Background: Four cardiac peptide hormones, namely vessel dilator, long-acting natriuretic peptide (LANP), kaliuretic peptide, and atrial natriuretic peptide (ANP) have anticancer effects. Materials and Methods: The effects ...