Master's Theses

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This collection consists of digital copies of master's theses submitted for degree at the colleges and departments of the Wichita State University. The collection includes theses beginning of fall 2005 and later.

The complete set of all WSU theses may be found in WSU Library Catalog. University Libraries has two paper copies of each theses submitted before 2006 and archival microfilm copies in the Libraries Special Collection for theses after 2006.

All items in SOAR are protected by copyright, with all rights reserved. They may be viewed from SOAR for any purpose, but reproduction or distribution in any format is prohibited without written permission of the Wichita State University. Contact: susan.matveyeva@wichita.edu

Recent Submissions

Magnetic and albumin targeted drug delivery for breast cancer treatment

Abedin, Farhana (Wichita State University, July , 2011)

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Abstract:	This research work involves multifunctional magnetically targeted drug delivery microspheres for treatment against breast cancer. A combination therapy approach was followed by encapsulating two chemotherapeutics, 5-Fluorouracil (5-Fu) and cyclophosphamide in poly(D, L-lactide-co-glycolide) (PLGA) microspheres. Magnetite nanoparticles and albumin were also incorporated in the microspheres to achieve targeted treatment. The microspheres were fabricated using oil-in-oil emulsion/solvent evaporation technique. Albumin is attracted to cancer cells and thus it is likely to draw the microspheres towards tumor cells. On application of magnetic field near tumor site, magnetites in the microspheres are likely to guide them to the region of magnetic field. This will allow release of drugs from microspheres in the cancer cells. Also the burst release of drugs and then slow release due to diffusion in the cancer cells lead to effective treatment and also limit excessive spreading of drugs in other regions of the body. Release rate study was carried out using high performance liquid chromatography (HPLC). Invitro and in-vivo study was carried out to check the efficacy of treatment.
Description:	Thesis (M.S.)--Wichita State University, College of Engineering, Dept. of Mechanical Engineering.
URI:	http://hdl.handle.net/10057/5054

Files in this item: 1

t11057_Abedin.pdf (2.314Mb)

Design and studies of azadipyrromethene appended donor-acceptor conjugates

Amin, Anu N. (Wichita State University, July , 2011)

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Abstract:	The research work presented in this thesis is comprised of syntheses, characterization, electrochemical and photophysical studies of aza-BODIPY appended donor-acceptor conjugates. The first chapter delivers an introduction to the research presented in the chapters that follow. It provides an overview of the primary events of natural photosynthetic processes, an understanding of which is essential for constructing artificial photosynthetic systems capable of harvesting light energy. The second chapter deals with photoinduced electron transfer processes occurring in the aza-BODIPY-C60 dyad and Ferrocene-aza-BODIPY systems. Femtosecond transient absorption spectroscopy showed efficient photoinduced electron transfer. In the third chapter (BODIPY)-aza-BODIPY dyad and triad were studied to explore the role of aza-BODIPY as an energy acceptor. Steady state optical absorption and emission studies revealed the occurrence of efficient energy transfer from singlet excited BODIPY to aza-BODIPY. Chapter four describes the supramolecular tetrad composed of aza-BODIPY, ZnP and fulleropyrrolidine, which was studied to explore both electron and energy transfer processes.
Description:	Thesis (M.S.)--Wichita State University, College of Liberal Arts and Sciences, Dept. of Chemistry
URI:	http://hdl.handle.net/10057/5053

Files in this item: 1

t11058_Amin.pdf (3.110Mb)

Electrospun nanofiber based biosensor for ultrasensitive protein detection

Anwar, Md. Rajib (Wichita State University, July , 2011)

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Abstract:	This research attempted to develop “label-free” biosensor for the detection of cardiovascular risk biomarker, C-reactive protein (CRP). An electrospun Polystyrene (PS)/ Polyaniline (PANI) nanofiber was used as the sensing element of the biosensor and coupled with electrical measurement system. High aspect ratio and porosity of nanoscale fiber provides size matched confinement for tiny biomolecule immobilization, which leads to rapid transduction and enhancement in signal strength. Nanofiber mat was integrated with a gold microelectrode interdigitated chip and microfluidic chamber to create a lab-on-chip platform. Results demonstrated that nanotextured fiber with appropriate chemical and electrical functionality can be used as sensing element of an electrochemical biosensor for detection of biomolecules at very low concentration. CRP was successfully detected at 100 fg/ml concentration from human serum suggesting the potential of this lab-on-chip platform for early detection of any cardiovascular risk. A large dynamic linear range of 100 fg/ml-1 μg/ml was achieved in human serum for detection of CRP. Less than 10% cross-reactivity with human albumin suggests the selective detection capability of the proposed biosensor.
Description:	Thesis (M.S.)--Wichita State University, College of Engineering, Dept. of Mechanical Engineering.
URI:	http://hdl.handle.net/10057/5052

Files in this item: 1

t11059_Anwar.pdf (1.002Mb)

Analysis of code-switching and code-mixing among bilingual children: two case studies of Serbian-English language interaction

Brezjanovic-Shogren, Jelena (Wichita State University, July , 2011)

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Abstract:	This research attempts to expose the patterns of language behavior of two five-year old bilingual children through the analysis of the code-switching and code-mixing occurrences in their everyday conversational interactions. The goal of the study is to analyze the code choice and the motivation behind such pattern in order to see whether there are any differences between the two case studies, and most of all, what is causing these differences in linguistic behavior to occur. Data used in analysis was collected during informal conversations recorded in home domain of the two families studied. The recorded data along with the observational notes collected was then analyzed sentence by sentence and separated into several dyads in order to understand the relation between the children‟s code-switching/code-mixing and the interlocutor. It is concluded that most common motivation behind their code choice is solidarity –establishing “we code”, referential, directive, and reactive to positive/ negative face and power. The major difference between the two children‟s language behavior regarding code choice is rather in the patterns of code-switching versus code-mixing. The boy, being a natural bilingual who acquired the second language (L2) simultaneously is more prone to code-switch in certain situations. On the other hand, the girl, who acquired L2 consecutively and therefore adopted the syntax of Serbian language, uses more code-mixing during her conversational interactions. This showed close connection of the linguistic behavior with the linguistic environment exposing essential mechanisms of children‟s ability to adjust their language skills to their conversational needs.
Description:	Thesis (M.A.)--Wichita State University, College of Liberal Arts and Sciences, Dept. of Anthropology
URI:	http://hdl.handle.net/10057/5051

Files in this item: 1

t11060_Brezjanovic Shogren.pdf (583.9Kb)

Phylogenetic analysis of the scarab beetle tribe Cyclocephalini (Coleoptera: Scarabaeidae: Dynastinae) based on adult morphological characters

Clark, Daniel R. (Wichita State University, July , 2011)

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Abstract:	The scarab beetle tribe Cyclocephalini (Coleoptera: Scarabaeidae: Dynastinae) includes 15 genera and approximately 500 species that are distributed primarily in the New World. Species in the group are important pollinators of aroids, palms, and lilies, some are agricultural pests, and a few are invasive in areas where they have been introduced. Evolutionary relationships of the group have not been examined, and monophyly of the tribe and relationships of genera have not been addressed. As a result, the classification remains unstable, and there is no foundation with which to interpret evolutionary patterns. To provide an evolutionary framework, a phylogenetic analysis using 77 adult morphological characters was performed. Representatives from all recognized cyclocephaline genera were examined as well as taxa that have historically been included in the tribe. Outgroups included exemplars from the dynastine tribes Oryctini, Oryctoderini, and Pentodontini and the ruteline tribes Anomalini and Rutelini. Based on the analysis, Cyclocephalini, as currently circumscribed, does not constitute a monophyletic lineage. Thus, the current classification does not reflect evolution, and revision is required. Based on strong character support, the genera Eriocelis and Stenocrates are not a part of the new cyclocephaline clade while genera Parapucaya and Neohyphus are members of the new Cyclocephalini.
Description:	Thesis (M.S.)--Wichita State University, College of Liberal Arts and Sciences, Dept. of Biological Sciences.
URI:	http://hdl.handle.net/10057/5050

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t11061_Clark.pdf (1.262Mb)

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