Wei, Liuqing; Gan, Xiangdong; Zhong, Jiaying; Alliston, Kevin R.; Groutas, William C.
(Elsevier, 2003-11-17)
A central problem associated with the design of enzyme inhibitors in general, and serine protease inhibitors in particular, is the identification of templates capable of binding to the active site of an enzyme in a predictable ...